The Largest Daily Dose of Warfarin

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The Largest Daily Dose of Warfarin

  • 25 mg per day or less

    Votes: 9 40.9%
  • 25 to 50 mg per day

    Votes: 6 27.3%
  • 50 to 100 mg per day

    Votes: 5 22.7%
  • 100 to 250 mg per day

    Votes: 1 4.5%
  • 250 to 500 mg per day

    Votes: 0 0.0%
  • More than 500 mg per day

    Votes: 1 4.5%

  • Total voters
    22
In 1962 it was regulated by watching for blood in the urine. If it appeared, the dose was "backed off some". My pharmacology textbook was copyrighted in 1960. It has only about 250 words about warfarin. It was the same text that medical students were using. This was 5 years after it was given to President Eisenhower. Just imagine the feeding frenzy that the news media would go into it it became known that President Bush took a medication that we only knew 250 words about.

I was giving a talk once in a small city where everybody in healthcare had covered for everyone else. They all knew a person who was taking 100 mg daily and was being managed by a hematologist at a university hospital.
 
So what happened, they added 25 words to it and called it updated and this is what they teach with today?
 
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