Statins & Memory Loss

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Statins, high cholesterol

Statins, high cholesterol

I am a dietitian, not registered, so this is in no way to be taken as medical advice. I read through many of these posts on this, sorry did not read all, too tired, son wont sleep.
First I am noticing many memory problems, muscle weakness in hands and body and difficulty with mixing up words, like I might say a word nearly backwards or say one word before the other in a sentance but in the wrong order. I only take coumadin asprin and Tiazac.
Anyway, if you have high cholesterol you can still have a heart attack on a chol. lowering drug, or still have continued build up of plaque in arteries to heart or carotid to brain. There is one proven (though most docs think he a quack) way to reverse the plaque and that is with a vegan diet. There is a book on it by (cant remember name, will post if I do) but this guy has the data to prove it in my book. Also it is hard to be a vegetarian on coumadin sometimes so another thing that will naturally lower cholesterol is flax seed. You put 2 Tbs, ground in OJ or over cereal, twice a day and it will work. Also eating raw nuts like almonds, cashews (RAW not roasted unless you do it yourself on low in oven) can do the trick. My husband does this and it works especially if you stick to more of a vegan diet. We live on raw nuts and seeds, salad, fruit, beans, whole grains, most of the time. Stress _ Ben and Jerrys and Mexican mayhem for us. Hope this helps and forgive if it did not make much sense, son had lots of seizures last night, did not sleep for 30 hours and I feel like crap. Hope this helps, if you want to private email me for info I have I will dig it up. My husbands doc told him he had a lady who had been on Lipitor for years and was currently in the hospital for quad bypass, her cholesterol levels were fine. Sorry to sound scary, sometimes there are more simple solutions that more mainstream medical docs dont hink of, believe or know.
Leighanne
P.S. This is not medical advice or instruction to be on a vegan diet, just ideas
 
Just got put on Pravachol today. My cardio believes that the studies by the Mayo Clinic are credible that taking statins slows down the process of calcium build up on valves. This may slow down the stiffining process of valves in people with stenotic valves (especially aortic valves). My cardio believes that anyone who receives a tissue valve (including autograft and homograft) should take a station drug as a preventative measure. So I'll take them as long as I tolerate them well, or until the next new study comes out proving something entirely different. :rolleyes:

I meant to add that I don't have high cholesterol, and lowering cholesterol does not seem to cause the beneficial effect of reducing calcium on valves. According to the study statins appear to reduce inflammation and cause calcium to be absorbed by the body's bones, which leaves less calcium in the blood to build up on your valves (or other areas).
 
Tobagotwo writes:
>>>>
Much of the recent literature states plainly that C-reactive protien is a far better predictor of cardiac events than cholesteral. There are standard tests for it. I've had numerous blood tests recently, and all have included cholesteral tests. None have ever included C-reactive protien, even though it's just a check-off on the form. Why? I suspect it's because they don't yet have a "treatment" for it. No treatment, no godlike stature, no testing clinic income, no new way to control their patient audience, nothing new to force compliance, no blockbuster drug income, all = no interest.
>>>>

Like you say Tobagotwo - many say homocysteine, c-reactive protein, fibrogen, and lp(a) may all be better markers. Like you say some of those can only be lowered by natural means that are not yet able to be patented so the incentive for Big Pharma to do studies on them hasn't materialized yet.

Dr. Linus Pauling, the double nobel prize winner, argued that cholesterol wasn't really the problem but rather deficiencies of vit C - Dr Pauling recommended vit C, lysine, proline to enable the body to repair the artery damage.

The problem I face personally is that in my reading of the evidence I personally would rather take my chances going with nutritional means to regulate cholesterol, and those other possible factors like LP(a), c-reactive etc. But my cardio is really adamant about everybody being on anti-cholesterol pharma products no matter what. My PCP says my cholesterol levels are OK. (My HDL was 82 - total cholesterol 219). I don't want to argue with my cardio, I just don't want to take the anti-cholesterol meds. Will he fire me as a patient if I don't want those particular meds? I'd like to keep going to this cardio as their coumadin lab is good and I need the prescriptions for the coumadin at least. The irony is my heart rate and BP will no dout be going up when I face this issue at my soon scheduled check-up.

Thanks for your advice Leighanne. I'm eating walnuts and almonds (the only problem is I like them with a big bowl of frozen vanilla yogurt, and I also eat chicken). I'd rather try the flax seed stuff than the anti-cholesterol pharma products.
The AMA journal JAMA had articles last year about lowering cholesterol via diet -
From:
http://abcnews.go.com/sections/living/Healthology/HO_eatlikeape.html
>>>>>
But a recent study that compares the two approaches shows that a diet that includes almonds and several other specific plant foods can lower cholesterol ? specifically LDL, the "bad" cholesterol ? as significantly as a leading cholesterol-lowering medication.

In the study, which was published in the July 23 issue of the Journal of the American Medical Association, researchers divided participants into three diet groups. One group ate a diet low in saturated fat, the second group received the same diet, along with a statin, and the third group ate a diet containing specific cholesterol-lowering foods.

Below, lead researcher Cyril Kendall, PhD, a research associate in the department of nutritional science at the University of Toronto, discusses how diet can quickly and safely reduce cholesterol levels, and whether people can learn to stick with it.
>>>>>


One irony is that with all the talk of the dnagers of high cholesterol there is little discussion of the dangers of low cholesterol. God designed our bodies to use cholesterol for a lot necessary functions and going too low on cholesterol poses risks. On the dangers of low cholesterol -

From:
http://www.mercola.com/2001/nov/24/cholesterol.htm
>>>>>
Cholesterol is Needed to Help Your Brain Cells Communicate

Cholesterol in your brain is key to the cell connections needed for memory and learning.
....
According to the researchers, these findings suggest that any "genetic or age-related defects" in the brain's cholesterol use may impair the circuitry behind mental functioning.

Science November 9, 2001;294:1354-1357
---------------------------

Dr. Mercola's Comment:

Cholesterol has for far too long been an evil villain. As the articles below show, low cholesterol is not something that is a desirable goal. A few years ago I thought I had a solution for it, but that never turned out to be something consistent. So at this time I don't really have any good clinical recommendations for those with low cholesterol.

However, it is clear that those on cholesterol drugs should not have their cholesterols drop much below 200 or they will be exposed to some of the risks noted in the articles below.

Related Articles:

Low Cholesterol Linked to Depression 3/26/00
http://www.mercola.com/2000/mar/26/cholesterol_depression.htm

Low Cholesterol Linked to Stroke Risk
http://www.mercola.com/1999/archive/low_cholesterol.htm

Low Cholesterol and Suicide Risk
http://www.mercola.com/2001/aug/8/suicide.htm

Low Cholesterol Causes Aggressive Behavior and Depression
http://www.mercola.com/2001/jan/14/low_cholesterol_aggression.htm

Low Cholesterol Linked to Depression 5/31/99
http://www.mercola.com/1999/archive/low_cholesterol_linked_to_depression.htm
>>>>
 
Update

Update

hensylee said:
this thread is a real concidence for me. I am on Lipitor and have been for more than four years. Some of you recall I had a different surgery last May and couldn't walk after the surgery - I may have been injured but don't know. I have been to every sort of dr, even chiropractor, gotten those bursitis shots, Celebrex, the works. Nothing helped so I just gave up trying to get help and figured I would always be crippled - it has been worse than the surgery could ever be. (The other day I remembered my cardio's nurse practitioner said a medicine vacation was ok for me when I told him I had stopped taking Lipitor a few yrs ago. Well after I stopped it, my numbers went back up - that was in 2000, so I started back on the Lipitor.) Since last year, my muscles have gotten so bad I haven't been able to walk much, I must use a cane and ride those carts in the store. A week or so ago I suddenly decided to just stop Lipitor (for no real remembered reason) and yesterday, I felt like walking down my (long) driveway - went part way without a problem. Today I went to local grocery and circled the inside of it just using the basket and walking along just like everyone else. I am not ok yet but I am hoping this change will continue and if it does I never want to see a statin again.

Tonight I went on the net to see what I could find about muscle damage from statins and lo and behold there it was. Do a search on LIPITOR MUSCLE DAMAGE and you will find what I did. There was one by a Dr Graveline who used to prescribe it freely until he discovered cognitive memory damage. (and I just thought I was a pumphead!)

It is so awful to not be able to walk freely and without help. I don't know if this is really the problem, but whatever it is, is getting worse all the time, so I am stopping the Lipitor and will just watch cholesterols - which I already do anyway.

I plan a vacation next month and sure want to be able to walk to all those spots my son and his wife have in store for me.


I posted the above in March this year and have not taken even one Lipitor since. Just thought maybe you'd like an update a couple months later.

As you can see, I could barely walk when I wrote that. I can now walk everywhere, have NO cramps, have not used a cane nor an electric store cart. It was so bad then that feet cramps would wake me from a sound sleep and I had to jump (?) out of bed and walk it out. Cramps were all over the place in my body. I can only attribute the improvement to the statin discontinuation. I am happy again and feel good when I wake up in the morning, looking forward to the beginning of every day. Before, I said many times during the night 'ow - s***' in my sleep and daughter could hear it in her room. I am not completely back to the old me, and never will be, but the results are amazing.

I cannot nor will I suggest that anyone do as I did and just discontinue ANY medicine prescribed for you. But please, if you are having problems of some sort that MIGHT be your medicine, go on the net and ask your questions. The answers are there.

Don't know what damage is being caused by the discontinuation of this medicine. There will be the regular blood test in a few months and if the cholesterol has gone back up, I don't know what in the world I will do. Keep watching the diet, I guess.
 
Glad to hear you're feeling improvement now. Thanks for sharing this. My Cardio is keyed up on the statins and I'd rather not take them myself - I guess I'll be taking some journal articles with me to my 6 month check-up to support my reluctance to take these meds and I guess I'll be looking for a new Cardio if he will not allow me to try an alternative route.
 
UPDATE

I went for six mo cardio check today and got a clean bill. I told him I had quit the Lipitor 2 months ago and was feeling so much better; looking forward to each day when I get up in the morning; am getting walking back in order; REFUSE to take any statin again. I'll just take my chances. He said I am one of those who can't take statins, but there's an alternative. It is ZETIA. Says it stops the body from absorbing cholesterol. I looked it up and side effects include stomach pain and tiredness. There are others but I don't know what they are. Any comments. Anybody?
 
Ann

Ann

My PCP keeps mailing me a scrip for them..Throw away.. :D Trying diet, exercise ( swimming everyday at pool..4 days in a row)I will not see him until Oct..Trying to lower tests..but sister and I compared ours..She is higher than me and her PCP didn't say anything about her taking them. I, know, heart,,but I don't have Heart disease..My arteries were :) clear 2 years ago..Cath scan....Yall should see the picture of ann when she graduated from High School. Hubby said, she should have gone to Hollywood. :) :) :)POST it, Ann... :D Bonnie
 
I have had an up and down course with statins for about five years now. I started out with Pravachol, 20mg and had no problems, but when my TCL only came down to 230, my doctor switched me to Lipitor. I found after 6 months on Lipitor that I was experiencing strange headaches or throbbings that went away when I discontinued it. Didn't take anything for about a year and the TCL went back up to 289, so last fall she put me back on Pravachol, but 40mg. In February, I found that I had severe leg weakness - painful to even walk around the grocery store. I have arthritic knees so I wasn't sure if it was that or something else. Stopped the Pravachol on my own and within one month it went away. I went back on the Pravachol but reduced the dosage to 20mg on my own. Haven't experienced the leg weakness yet. Blood work just came back last week and TCL is down to 240. You guessed it - she's not satisfied and said I could either increase the dose back to the 40mg or continue taking 20mg and add Zetia. She said it has very few side effects and only one patient has complained of stomach aches. I opted to try the 40 mg of Pravachol again first before adding a new drug. Can't help thinking that twenty years from now they will tell us about all the horrible things these statins do as they recently did with hormone replacement - thank goodness, I didn't take that! I'm 61 with no heart disease, but there is heart disease in my family. Dad never had high cholesterol and had his first heart attack at 40, Mom had high cholesterol and developed heart failure in her 80's. It's a quandry and hard to fight the doctors when they are so gung-ho on the statins. **** was put on 10mg of Lipitor after his AVR in December on the theory that statins will help keep the new valve from calcifying. Well, his cholesterol was low to begin with and in two months it went well below the reccomended levels. We decided to stop it on our own and his local cardiologist agreed.
 
Posted by Bonnie:

"picture of ann when she graduated from High School

I am copying Mara. I have already sent it to Ross a couple days ago to make it into an avatar til I can work up a more current (present day) one. My other one (above) isn't valid anymore. It's somebody else. :D
 
Anne - I've been on Zetia for about three months now and have had no problems in regards to side effects. I had blood tests at the two month time period and my Cholesterol numbers came back the best they have ever been, so I beleive it must be doing some good. I have tried most of the statins and have been plagued with leg cramps. I'm currently back on Zocor (which seems to cause the least amount of problems) and am taking a reduced dosage. I agree that the docs are gung ho on the statins, but with good reasons. The clinical trial data is very encouraging. As to the long term effects - who knows. When my legs start to ache, I'll cut back again. :cool:
 
Chris - you have any stomach pain with Zetia? I have taken two doses and 24 hrs after first dose, there was some pain and again the next 24 hrs later with second dose! Could be something else, I guess, but this is new. My stomach tends towards ulcers so I must be very careful about what goes in there. Just wanted to know.
 
Anne - I have had no stomach pain with Zetia, but that doesn't mean you won't have problems. Continue to monitor it carefully, and let your doc know what's going on. I'm really glad to hear you are getting around much better. :)
 
Whew, never have I read so much on one thread, ever. It was confirmation however, for my years of side effects on the statins. Don't think I would ever take them again. Some things just ain't worth havin'.

My muscle weakness is just NOW getting closer to normal, after 1 year off of Lipitor. Like Crawford, I have tried them all, but usually at about the 6 month mark, I have unbearable cramping and weakness. I remember squatting down in the grocery store to read some Tea labels, and could NOT get up. Couldn't. I was SOOOO embarrassed. Dad finally came around the corner and had to help me. I am 5' tall and weigh 110 lbs. Couldn't even lift my own body. THATS when I quit the statins. Within about 3 months I was better and now, I can squat, do stairs, no more cramps at night.... amazing difference. That was the only "drug" difference. Don't know what else it could have been.

Hensylee, don't give up on progress. I am STILL progressing, and so gosh darned happy that I am almost normal! Well, you know..... as close as "we" get to "normal"....
mindy ;)
 
Thank you, Mindy - I will expect continued improvement after your post. Really, it is just amazing. Who would have thought? At least now I have a partner in this belief - somebody else who has actually done it, too.
 
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