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CoQ-10 should lower INR but I've never used it.



From a reliable resource:

Regarding INR results. there is NO standard for INR results EVEN between lab devices. Alan Jacobson did a study looking at several LAB devices and the results are referenced in the following technical bulletin on the HemoSense web site:

http://www.hemosense.com/docs/5500258_TechBull103_INR_ISI_revB.pdf

As you can see any brand of handheld device is shooting at a moving target depending upon which LAB device is being compared against. Then when you consider there could be any number of additional possible sources of variation it can lead to a lack of confidence in the monitor.

Additionally, I'd like to point out the following chart available on the Roche site regarding duplicate testing using their strips and their monitor.

http://www.coaguchek-usa.com/product_notification/index.html

HemoSense has the same +/- 30% standard, but I feel it's important for patients to understand that this is the level of technology that is currently available for patient self testing as well as in the office environment. All manufacturers make good reliable devices and it's really (in my opinion) a matter of which monitor works best for each consumer based upon feature preferences.

I'm not a scientist, but I came across this on the U.S. Trademark and Patent site the other day. It appears that Dade is trying to create what would amount to a standard for INR testing at the lab level. This would be a tremendous step forward for the industry.

United States Patent Application
20070020765

Kind Code
A1

Zander; Norbert ; et al.
January 25, 2007



--------------------------------------------------------------------------------

Procedure for the standardization of coagulation tests

Abstract

The present invention lies in the field of coagulation diagnosis and relates to a procedure for the standardization of coagulation tests, where calibrators are used to which a discrete standard coagulation time is assigned. The procedure is particularly suitable for the standardization of prothrombin time, activated partial thromboplastin time, thrombin time, ecarin time or batroxobin time.
 
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