epstns;n867428 said:
I call this another case of "figures never lie, but liars often figure." Sure, they can show data indicating that a large percentage of middle-aged or older tissue valve patients never have a re-op, but when they calculate their survival stats, do they eliminate all deaths from non-valve-related causes? (e.g. Do they present a "relative survival rate?") If not, this is not a valid conclusion. If they do, then they may have a case. But then, how many of those seniors who have failing tissue valves have other conditions that preclude another surgery, or they are simply inclined to let things go their course? All of this could distort the statistical relationships the authors are trying to promote.
Good point about relative survival rates. That article doesn't mention them, but they are easy enough to come by. Here's one with a nice graph that even includes some location data for comparison (apparently, Canadians tend to live longer than US citizens):
http://www.sciencedirect.com/science...22522308015729
The whole article is interesting but scroll down a bit and you'll find a graph with information about relative survival rates post-AVR, with regard to age at implant, valve type, and country of origin (Canada, UK, or USA).
Again, not much difference in lifespan post-AVR between mechanical and bioprosthetic valves.
The older you are when you have AVR done, the closer to a normal lifespan you are likely to have. A 50 year old who needs AVR surgery can expect to have about 10 years shaven off of his lifespan (about the equivalent of being a lifetime smoker). For a 60 year old, it's less of a haircut -- closer to 5 years.
Edit: Note that this graph seems to assume an average lifespan of just over 70 years for a US citizen who makes it to the age of 45. That average lifespan has gone up significantly -- it is unclear how that has affected the AVR population.
Now there are other studies I have seen that look at what factors influence average lifespan after AVR. For example, you REALLY want to avoid having a-fib if at all possible if you are an AVR recipient -- I have seen more than one study revealing it to be the single most detrimental factor when it comes to lifespan post-AVR. Meanwhile, if you have a highly functioning heart at the time of AVR, you have much better long term prospects -- in some cases and at some advanced ages, even better than the general population!