Good morning
Sun just coming up here in (my part of) Australia, and I like going for an early morning walk in the wintertime to escape the cold of the house; so I'll try to be brief.
Pellicle, not to sidetrack this thread, but do you or others here think that lot's of activity wears a bio valve out early? I realize the medical establishment leans to a no answer.
nicely phrased question.
So, my short answer is yes; but its probably not what you think.
I don't think its just related to the pressures the valve experiences and increase in frequency of actuation (mechanical wear) that does it. Instead I believe its related to the associated biochemistry of the cocktail of things circulating around in your blood.
First lets say there are correlations and causations. Sometimes correlations are indicators that causality is there and we should look for it, other times its just only that - correlation.
That its only correlation is usually cleared up with more data. There is clearly a causal link between Structural Valve Degradation (SVD) and youth. This is well known and not subject to any leaning in the scientific community (I say scientific because surgeons are not the ones who research, design and make valves; they just stitch them in).
If you read up on SVD (I recommend
this link as an excellent roundup from 2020) you can see that a lot of what causes SVD is directly related to exersize generated biochemistry. In short the mineralisation of the "piece of leather flap" that is essentially what a bioprosthesis is gets attacked by the biochemistry of the living body.
Much of this slows down with age of course, but it is my view that it slows down less in people who are active.
Next you should look at the physiology of the native valve, and observe key points like "cellular regeneration".
This article is a deep dive but depending on your patience in reading such things is very informative. I'll snapshot a good point
Basically the structure of the native valve is such that the tissue is not only regenerative but very flexible, its not "vascularised" (like skin is) because its permanently immersed in a bath of the freshest blood. If its not then you have broader systemic problems ;-)
Anyway I recommend you read that pointer to SVD in the first link and then get further down to
Strategies for SVD Prevention. Note these are at the manufacturing stage and note also the words: "
Its exact mechanism is unknown".
This leaves us with "more research is needed" as well as the basic observable facts (called statistics), such as the onset of SVD based on age and the interesting observation that all bio-prosthesis manufactures seem to like terminating their research into longevity of valves at 10 years. Perhaps that's because they think that the median age is in the mid 70's for valve replacement. I googled that exact question and got this:
What is the average age for aortic valve replacement?
The mean age in the study population was 75.1 ± 6.6 years
So since that's their market that's what they make. Questions of "will it last longer in young active, sporting and fit 60yo" are not of interest to them.
Thus we are left to conjecture. So, look around this forum and see how many of the fit active sporting weight lifting types have mechanical, and which have tissue.
HTH
Best Wishes