Search results

Valve Replacement Forums

Help Support Valve Replacement Forums:

This site may earn a commission from merchant affiliate links, including eBay, Amazon, and others.
  1. H

    Heart problems for grandson

    Hi Mr V. Our daughter had OHS three days after her birth. She had transposition, interrupted aortic arch, a leaking aortic valve and vsd. We also found out during a standard ultra sound and I can fully relate to the thoughts and emotions you and your family is going through. She's 15 now and...
  2. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    Yes, that's probably it. Thanks for helping me out with reflecting.
  3. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    Reading and analyzing research data on a daily basis has been a part of my job for the last 15 years so I feel pretty at home. (Not about heart valves and warfarin though.) The more you learn, the more humble you get too however, due to understanding how often you make mistakes and how little...
  4. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    Lowering IT and Proact is strictly looking at Mechanical valves. The dutch also includes Atrial Fibrillation and Myocardial Infarction (majority of patients). It wouldn´t be fair or give us any valuable information to compare LowIT and Proact to something different then they try to answer...
  5. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    Dutch: 483 patiens for 1.149 p-years (Mec Valve) Lowering IT: 396 patients for 2.217 p-years Proact: 375 patients for 1.426 p-years
  6. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    I wouldn't discharge the age difference in age as of low significance. Lowering IT mean age 49, Proact 55. The dutch is not giving us a clear mean age but viewing how they diveded age groups it's clear it's a significant older population. Specially since most research would say risk of events...
  7. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    The tabel you posted above is this, right? Being used in thus study from the Netherlands: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/415179 So I assumed it to be "the dutch stud". Hope I'm not totalt out of bounds here 🙂
  8. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    https://pubmed.ncbi.nlm.nih.gov/20598989/ It's the Lowering IT study you linked to in your earlier post regarding the 1:3 ratio.
  9. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    You mean 26 events per 100 patient years, right? If you refer to "The dutch study". Or am I missing something? Also note: out of the 38 total bleeding events, 11 is "Nonfatal bleeding in skin and muscles". They adopted the event labeling from an even older study and "Nonfatal bleeding in skin...
  10. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    This is actually numbers from the Lowering IT - study from 2010. No On-X there.
  11. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    Yes. It tells us this is probably a bit more complex than we would wish it to be. We'de probably need to look at more individual factors on all of the patients to know what's really going on. You can also find in the study that both group have a couple of patient years below INR 1.5. I can't...
  12. H

    400 person study on lower INR (1.5-2.5) with mechanical valve

    It's actually the other way around. They had 1 TE in the Low-INR and 3 in the standard.
  13. H

    My 15 yo daugther - soccer dreams on warfarin

    Sad but probably true...
  14. H

    My 15 yo daugther - soccer dreams on warfarin

    Wouldn't take any news channel as medical advice at all. 🙂 But still this is all you know about warfarin untill you start to research it. No wonder people fear it so much. Pro athletes (supermen) can bleed to death by a cut??? 😵‍💫
  15. H

    My 15 yo daugther - soccer dreams on warfarin

    Good link. Thank you.
  16. H

    My 15 yo daugther - soccer dreams on warfarin

    And yet you read atricles with text like this: "The sticking point is if Bosh is able to play, safely, while taking blood thinner medication. Understandably, the Heat are being very cautious. If Bosh were to get cut while taking blood thinners, it's not an exaggeration to say that he could die...
  17. H

    My 15 yo daugther - soccer dreams on warfarin

    You make me realize I over-use that crazzy-term. Probably due to lack of vocabulary :) And shouldnåt be my main focus here. Most people would probably say both me and my daughter is very rational and "low emotional" about this so it´s probably meusing wrong words in written english. How did...
  18. H

    My 15 yo daugther - soccer dreams on warfarin

    I´ve found some pro athletes training on warfarin and also competing/games on NOACS but not yet any player in contact sports playing fully on Warfarin. Anyone that knows of someone doing this?
  19. H

    My 15 yo daugther - soccer dreams on warfarin

    What you say is pretty much what I "see" too when I study these topics. I´m besides, reading research about warfarin, reading about risks for IC in "normal population", heading statistics, stroke numbers, what other factors are effecting bleeding risks etc etc. And what I find, very much relates...
  20. H

    My 15 yo daugther - soccer dreams on warfarin

    If all headers, under all conditions, must be equal to absolute zero, then soccer is out of the picture. You can reduce it a lot but you just can´t make it zero every time you play, the way the game is being played. You can kick around a ball in the garden without ever heading, but you can´t in...
Back
Top