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Hi, does this mean you needed a surgical fix to your bovine valve? So sorry to hear.

Merry Christmas everybody. I would like to thank everyone on this great forum for helping me to get through a tough 2022 (2nd AVR). It was much easier to make a choice and persevere reading all of the very helpful advice on this site.

Fingers crossed for Thursday. Please do let us know once you are on the other side. Best Wishes.

So the quality of any individual propensity matched study depends on the data available to match patients. National registers usually have less data on individual patients than hospitals. If you look at those propensity score matched studies done by hospitals...

Hi Raoul, I was in your shoes when I just turned 33. I had my first surgery with a bio valve back then. I just had my second heart surgery in May to get a mechanical valve (I couldnt have a Ross due to large aortic annulus). I found that the hardest thing is actually making a choice that is...

I would suggest bringing warm clothes. I am 41 and I kept feeling cold in the room. A good book that will distract you. and perhaps a tablet to catch up with your family at night. (My family caught covid the day before I went in, so most of them were not able to come and see me and we just...

WOW really super helpful. Let me read and digest. I did indeed start to reduce my dose a bit to account for this. Thanks Tommy

Thanks very helpful. I will try and look for a different culprit

Hello team, does anyone have experience with how paracetamol (Tylenol) affects your INR? My INR recently jumped from 2.1 to 3.1 within four days after I started taking paracetamol for tooth ache. Did anyone else have a similar experience? Thanks Tommy

Hello, There is actually a recent randomised control trial to answer the On-X vs St Jude question. https://www.sciencedirect.com/science/article/pii/S2666273622003084 It concludes: 'The On-X valve and St Jude Medical valve performed equally well in the study with no differences found.'. Now...

I can't explain this and you are right to pick up on it. Also doesnt explain how Arnold Schwarzeneger had a TAVI 23 years after this Ross (but then again we dont know what happened when his ross failed the first time - whether they repaired the autograft or instead put an Aortic Homograft...

I am fairly recent Mech valve person, so I think that comments from the other forum participants are prob more valuable than mine. We are similar in age. I am 41 and just had my second surgery (this time mech valve) in May. When I had my first surgery (Mech valve was second), I was also pushing...

Hi John, Short Answer: There have been two randomised control studies that randomised patients into a mechanical Bjork-Shiley and bio valve. If you look at these trials, the risk of stroke, endocardities etc is the same across valves. Mech valves in these trial had a roughly 2% chance of bleed...

Hi John, I am also in the UK and recently had my second surgery. I am 41 and received an ON-X mechanical valve. The surgeon I chose only offered Carbomedics or ON-X valves, and because this surgeon had an outstanding track record, including in complex re-operations, I ended up choosing the...

Another interesting way to look at the event rate of 0.5% of thromboembolic event per year and compare it to the incidence of stroke in the General population. The paper below suggests that the life-time incidence of stroke in someone aged 50 is roughly 20% in the general population...

Hi Team, I came across this great website to make evidence appraisal easy for clinicians: NERDCAT They also have an interesting analysis of the ON-X valve PROACT trial: https://nerdcat.org/studysummaries/proact They say (the bold is from their analysis, ie not me): Based on the 95% CI, the...

Fully agree that care is required with the On-X lower anticoagulation regime. If you look at the 'low-risk' patients in the PROACT trial, nobody appears to have had a stroke on standard warfarin therapy (exhibit B). Obviously, there is less observations as you go out, and I would say that the...

Hi Team, The PROSE trial, a randomised control trial between ON-X and St Jude valves, have now published their results. https://www.sciencedirect.com/science/article/pii/S2666273622003084 From the abstract: The total patient population (N = 855) included patients receiving an On-X valve (n =...

Can you see the display well? I had the Charge 3 and the display was very dim. I could barely see it most of the time. Then it died after three months of use. So does teh Charge 5 have a good display? Can you see it in direct sunlight and in the dark? Thanks

Hi Chuck, the Polar strap is actually the one piece of kit I have. I also used to have issues with it connecting to the app on my android phone. I managed to solve these issues the following way: 1) Make sure that you connect the device via bluetooth in the App first (no via your phone's...