This was reported in another thread. It's titled 'Partner cohort....." and it's in the Heart Talk thread. It's quite interesting.
The speculation is that it may also be useful for younger, healthier people who would be at less risk of death during surgery.
There are more studies to be done, and there are still many questions to ask, but it seems promising -- especially if it's an only option for many who aren't candidates for open heart surgery.
Any study design could be considered statistically challenged - in most cases, subjects are put into random groups -- with some getting the new, experimental treatment and others getting current treatment methods. In this case, if the person isn't getting this new valve, the other option is surgery -- and those physicians would obviously know the difference between inserting a new valve through an artery and splitting a patient's chest wide open. OTOH -- those surgeons doing either arm of the study would be focusing on the best possible outcome.
It'll be great if this valve can outlast the body of the person carrying it (in other words, cause of death will be OTHER THAN valve failure), and that it doesn't eventually wear out or require long term anticoagulation. If, one day, a person with a bad valve can just check in to the hospital for an overnight procedure, this would be great. It'll eventually make it easy to tell which patient had OHS and which ones didn't because there would be no sternal scar i those who didn't have OHS.