INR like a yoyo

[Ross]

I would have to think the 4.9 was a bogus result.

 

[Newbie]

Thanks for all your input.

Update:
Recap: Monday - 4.9
Wed - 1.8 (prescribed 3 days of Fragmin + increase in dosage)
Friday - 2.0 (first home test)
Monday - 2.3 (home test)
Wed - will be a Hospital vein test + will do a home test at same time to see if machine is right...

 

[Freddie]

Freddie - Do you know who the Manufacturer of your Generic Warfarin is?

Frankly, I am rather surprised by this conclusion as The Vast Majority of patients who have switched from Brand Name Coumadin (did you know there were Several Sequential Owners of that Name?) to Generic Warfarin have seen NO verifiable difference, at least those who have switched to the Generic Warfarin manufactured by Barr (USA) or TARO (Israel) who are Highly Respected Manufacturers of Generic Warfarin.

'AL Capshaw'

Sorry Al for not responding sooner. My new generic warfarin is TARO, it use to be APO and we all know what happened while I was on it.

 

[Ross]

Thanks for all your input.

Update:
Recap: Monday - 4.9
Wed - 1.8 (prescribed 3 days of Fragmin + increase in dosage)
Friday - 2.0 (first home test)
Monday - 2.3 (home test)
Wed - will be a Hospital vein test + will do a home test at same time to see if machine is right...

Something still isn't right. Can you post exactly what your taking each day? It sounds to me like your testing way too much and changing the dose too often.

 

[Newbie]

Dosage

Dosage

Something still isn't right. Can you post exactly what your taking each day? It sounds to me like your testing way too much and changing the dose too often.

I was testing often because the machine is new. New toy. I don't change my dose.

June - 5 mg
Day - Dose - INR
15 - 0.5 - 2.64
16 - 1.5
17 - 1 - 1.66
18 - 2
19 - 1.5
20 - 1.5 - 2.06
21 - 2
22 - 1.5
23 - 2
24 - 1.5
25 - 2 - 3.03
26 - 1.5
27 - 2
28 - 1.5
29 - 2
30 - 1.5
1 - 2
2 - 1.5
3 - 2
4 - 1.5
5 - 0 - 4.9
6 - 1
7 - 2 - 1.8 + 1 injection of fragmin
8 - 1.5 + 1 injection of fragmin
9 - 1.5 + 1 injection of fragmin - Home Test 2.0
10 - 1.5
11 - 1
12 - 1.5 - Home Test 2.3
13 - 1.5
14 - TEST AT HOSPITAL

 

[dick0236]

I was testing often because the machine is new. New toy. I don't change my dose.

June - 5 mg
Day - Dose - INR
15 - 0.5 - 2.64
16 - 1.5
17 - 1 - 1.66
18 - 2
19

Just curious but what do the numbers .5, 1.5, 1, 2 etc under the header "Dose" mean?

 

[Bill B]

The 4.9 looks more and more like an anomaly.

 

[ALCapshaw2]

Sorry Al for not responding sooner. My new generic warfarin is TARO, it use to be APO and we all know what happened while I was on it.

Hope that solves your issues Freddie. FWIW, I've never heard of APO.

TARO is a highly regarded manufacturer of Generic Drugs in Israel.

My first 'mail-order Rx Provider used TARO. There was NO noticable change when I switched from Coumadin to Warfarin from TARO (and later to BARR) due to changes in providers / coverage by my company's Rx Insurance provider.

 

[Newbie]

Just curious but what do the numbers .5, 1.5, 1, 2 etc under the header "Dose" mean?

Each Pill is 5 mg. 0.5 is half a pill or 2.5mg.. 2 are two pills or 10mg and so on...

 

[Newbie]

The 4.9 looks more and more like an anomaly.

I'm thinking the same .. Resutls from today:

INR still low...1.78 New dosage for 7 days

Date
14 - 2.0 - 1.78 + STOMACH INJECTION OF FRAGMIN FOR 3 DAYS
15 - 2.0
16 - 1.5
17 - 2
18- 1.5
19 - 2 --- CATHETER TEST TO SEE IF THERE IS A BLOCKAGE SOMEWHERE, if so, possible stent...
20 - 1.5
21 -- HOSPITAL TEST

 

[Ross]

What is the total weekly dose?

 

[dick0236]

Each Pill is 5 mg. 0.5 is half a pill or 2.5mg.. 2 are two pills or 10mg and so on...

I understand. If my math was correct....these were the amounts per week:

6/15-6/21 you took 50mg INR 2.1 on 6/20
6/22-6/28 you took 60mg INR 3.0 on 6/25
6/29-7/5 you took 52.5mg INR 4.9 on 7/5
7/6-7/12 you took 50mg INR 2.3 on 7/12

The 4.9 may have been the result of the increase to 60mg, or it may be just a fluke. Hard to say, but it appears you are changing daily dosages too often, but not terribly. If it were me, and I wanted to be in 2-3 range, I would stick with 50mg/wk(6 days @ 7.5mg + 1 day @5mg for a week or two). If you want to be in 2.5-3.5 range, you might try 55 mg/wk(6 days @7.5mg + 1 day @10mg for a week)....and restes after one week of change. Once you home test, this stuff becomes "a piece of cake".

And I repeat, I am not a doctor, and this represents only what I would consider doing:angel:.

 

[Ross]

I understand. If my math was correct....these were the amounts per week:

6/15-6/21 you took 50mg INR 2.1 on 6/20
6/22-6/28 you took 60mg INR 3.0 on 6/25
6/29-7/5 you took 52.5mg INR 4.9 on 7/5
7/6-7/12 you took 50mg INR 2.3 on 7/12

The 4.9 may have been the result of the increase to 60mg, or it may be just a fluke. Hard to say, but it appears you are changing daily dosages too often, but not terribly. If it were me, and I wanted to be in 2-3 range, I would stick with 50mg/wk(6 days @ 7.5mg + 1 day @5mg for a week or two). If you want to be in 2.5-3.5 range, you might try 55 mg/wk(6 days @7.5mg + 1 day @10mg for a week)....and restes after one week of change. Once you home test, this stuff becomes "a piece of cake".

And I repeat, I am not a doctor, and this represents only what I would consider doing:angel:.

If that is indeed the case, I would agree.

 

[Newbie]

I understand. If my math was correct....these were the amounts per week:

6/15-6/21 you took 50mg INR 2.1 on 6/20
6/22-6/28 you took 60mg INR 3.0 on 6/25
6/29-7/5 you took 52.5mg INR 4.9 on 7/5
7/6-7/12 you took 50mg INR 2.3 on 7/12

The 4.9 may have been the result of the increase to 60mg, or it may be just a fluke. Hard to say, but it appears you are changing daily dosages too often, but not terribly. If it were me, and I wanted to be in 2-3 range, I would stick with 50mg/wk(6 days @ 7.5mg + 1 day @5mg for a week or two). If you want to be in 2.5-3.5 range, you might try 55 mg/wk(6 days @7.5mg + 1 day @10mg for a week)....and restes after one week of change. Once you home test, this stuff becomes "a piece of cake".

And I repeat, I am not a doctor, and this represents only what I would consider doing:angel:.

Looking at it from a weekly doses perspective makes a lot of sense and simplifies the whole concept. Thank you !!

I'm trying to be in the 2.5 to 3.5 range, so 55 mg probably looks good.

 

[Arthur]

There are specialized anticoagulation clinics in Europe to take care of this rare but very known problems of anticoagulation dosage. You should find one in Montreal. This is important for you.

 

[Ross]

There are specialized anticoagulation clinics in Europe to take care of this rare but very known problems of anticoagulation dosage. You should find one in Montreal. This is important for you.

Dosing isn't rocket science. It's either poor management, something the person is putting into their mouth or another medical condition not yet discovered.