Dear Al Lodwick

Valve Replacement Forums

Help Support Valve Replacement Forums:

This site may earn a commission from merchant affiliate links, including eBay, Amazon, and others.
A

angela

Thank you for posting an answer to my son Kamal.
Yes, my husband is at the hospital since 18 days ago, and he has a very accentuated purple toe syndrome.
It started at about two weeks from leaving the hospital after a heart surgery for implant of metal valve (St. Jude - aortic position), and after being in treatment with Coumadin.
Firstly it was just a slighty blue-purple color in his toe nail, and then it appeared as though he was with Livedo reticularis. Both sympots increased very rapidly, until he finally was hospitalized 18 days ago, so that the doctors can treat him better.
Since the hospitalization, the coumadin has been suspended and so all the other medicines that he was taking (such as Lipitor, atenolol, Amiondarona, Norvasc and iron tablets that he also taking.)

A therapy with Enoxaparin (heparin - low molecular weight) has been started since then, but the purple allergy has only increased, and extended also to his both feet and legs, so the doctor also introduced Plavix (anti platelet aggregation drug).
It appears that the allergy has exarcerbated. So this weekend (Friday) the doctor started using cortizone, and also Balcor, since his blood pressure started to oscilate and make peak of 160/110. A sublingual medicine to bring down the blood pressure was also given.

The problem is that now with the cortizone, it appears as for moments the purpleness gets better, but yesterday, right after giving him the sublingual medicine for the blood pressure he had a very scaring reaction: his face, nose, fingers and toes went very purple, but after one hour or so, it dissappered again. When he is in "resting position" with his legs, the purpleness gets better. But in standing position goes worst.

It appears to me as though his allergical reaction to the Coumdain is being exacerbated with the use of Heparin and Plavix, and I am very much afraid about the complications taht it may bring.

Please give us your opinion on this.
Doctors here are thinking that perhaps EXANTA (ximelagatran) might be a way out this problem. But as you know, this medicine is still in trial phase and has not been approved by the FDA. We live here in Brazil, my husband is American, and we are going desperate over the situation.
Thank you very much, and thanks to all those who answered to my son Kamal.

Angela.
 
Angelia

Angelia

It is a long weekend in America .for Holiday..I'm sure more members will chime in this week..We have another active member..deboraginastewart..Lives in Curitiba..parana..Brazil..If you look at the top of our forum..you will see a member's list..click on D's..scroll down to her name..click on..There you will see where you can e-mail or PM..her... I hope your Husband finds some help soon. Bonnie
 
I am far from an expert on purple toes syndrome. I do not think that PTS is not an allergic reaction to warfarin. Has he been checked for the Ig mediators of allergies? I know even less about this but it would be a clue as to whether or not it is an allergy. If he has been off warfarin for about 18 days, it seems unlikely that it would be an allergy still causing this much problem. It does not seem like the toes would improve when they were elevated with PTS.

Has he been checked for heparin-induced thrombocytopenia? If this is the case, the platelet count would likely be less than 150,000. Should that be true, he needs to have all heparin products stopped immediately. This can occur even with enoxaparin and starting warfarin while someone has this can lead to amputations.

I think that he needs to get to a major medical center where there is a hematologist who specializes in clotting disorders. Most hematologists are also oncologists and are more up-to-date on cancer treatments than clotting disorders.
 
Aqui estou eu!!

Aqui estou eu!!

Oi Angela, tudo bem? Antes de qualquer coisa quero dizer que já estava mais doque na hora de aparecer mais alguém do Brasil por aqui! LOL!! Muito prazer, sou a Débora mencionada acima! Nasci em Joinville/SC, mas fui criada aqui em Curitiba. Sou casada com um escocês há vinte anos e temos uma filha chamada Bruna de oito, mas essa é uma longa história que te conto mais pra frente! No que diz respeito a esse site, você veio buscar ajuda no lugar certo, e se não fosse por esse pessoal maravilhoso aqui, não sei como eu estaria lidando com a questão da minha quarta troca de válvula mitral que deverá acontecer dentro dos próximos dois anos aproximadamente. Como eu sempre coloquei prótese biológica, não sou a pessoa mais indicada para te ajudar a exclarecer tuas dúvidas, mas quero que saiba que estarei torcendo para que tudo acabe bem, e acho que o Al cogitou algo importante e que deve ser levado em consideração.Você tem yahoo messenger ou skype? Eu adoro bater papo e ficaria muito feliz em poder conversar com você também. Tenho uma amiga que arrumei aqui cujo o marido operou em março desse ano, e embora ela more na Nova Zelândia onde a diferença de horário é de 15 horas com o Brasil, conversamos todos os dias, e às vezes até duas vezes! LOL!! Se você quiser, fique à vontade para me mandar um PM ou E-mail para: [email protected], e meu yahoo ID do messenger é deboraginastewart1
Bem, espero ter notícias tuas e do teu marido em breve. Seja bem vinda aqui onde não só falamos sobre coração, mas também temos o SMALL TALK(conversa fiada) onde podemos falar sobre diversos outros assuntos.
Durante o feriado estarei em casa, mas na sexta irei para Joinville para o aniversário da minha vó no dia onze.
Fique com Deus!
Débora :)
 
Back
Top