carolinemc
Well-known member
My lab that uses that, when I went to 100, I had to go to the regular lab in the hospital and get a draw from the arm. My reading in the lab was 4.0. The other lab concurred the same, and we dosed accordingly.
Highest INR you have heard of or experienced?
- Thread starter thomas999
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You had an INR of 100? 10,0? Was it the Coag-Sense that gave you that high INR? (IIRC, the Coag-Sense won't give a reading above 8.0, or maybe 9,0)
thomas999
Well-known member
It was actually over 100, probably 120. This was measured by the local hospital lab, and in the emergency room at the hospital. I remember talking to a nurse who said that's impossible because it can't go over 100. I don't know why she would think it stops at 100, but the PT value peaked at over 12. I was starting to bleed out from all soft tissue in the body. I often wonder if there was bleeding in the brain, but I am no crazier than I was before, at least that's what I think, haha.
pellicle
Professional Dingbat, Guru and Merkintologist
Lisa from LJ
Well-known member
I think your numbers are backwards. PT number is significantly higher than INR number. A PT of 100 would be an INR of over 15. An INR of 100 would be a PT in the 400s.
Lisa -- this makes a lot more sense than an INR of 100. And, FWIW, calculating the INR from the PT depends on the reagent value. The PT is divided by the reagent value to determine the INR.
FWIW - years ago, I was told by a clinic (probably mishandled my sample) that my INR was 7.1. I was careful for a few days, just in case the value was right My continued regular dose brought my INR back within range. I suspect that the lab was wrong - or the sample was mishandled so badly that an erroneous result was obtained.
(If the hospital got an INR of 100, it would have/should have, re-run the test immediately.
FWIW - years ago, I was told by a clinic (probably mishandled my sample) that my INR was 7.1. I was careful for a few days, just in case the value was right My continued regular dose brought my INR back within range. I suspect that the lab was wrong - or the sample was mishandled so badly that an erroneous result was obtained.
(If the hospital got an INR of 100, it would have/should have, re-run the test immediately.
Yeah, I was just reading about the interaction with Amiodarone and Warfarin. At my husband's dosage he should be taking a 30% lower dose of Warfarin due to the interaction. So when he comes off of it, next month if he stays in normal sinus rhythm for that period, then they will have to completely revamp his dosage. Right now he is on 5mg two days a week and 2.5 the other 5. His inr spiked up to 4.8 in the second week out of the hospital.
pellicle
Professional Dingbat, Guru and Merkintologist
I think this is perhaps not the right way to look at it. Yes there is an interaction BUT for as long as you're on it you just need to think one way:
the intention to treat with warfarin is INR
nothing more and nothing less ... the dose is only the bus number you take to get to that destination. That's all there is to it really ... keep within range.
This decision flow chart is from this post
https://www.valvereplacement.org/threads/complications-post-surgery.889636/post-934334
I think the information there about Paracetamol (Tylenol is one brand) is also beneficial knowledge too.
Best Wishes
Lisa from LJ
Well-known member
You're correct about the reagent. I used a calculator with an average value, but didn't use exact values for that very reason.
Lisa from LJ
Well-known member
True. I'm not sure it's even physically possible to have an INR of 100 without bleeding out from all parts of the body.
