What is normal?

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KLB123

I see posts with all these different INR #'s and was wondering what a "normal" INR is?
 
A "normal" INR = 1.0 The in INR is a ratio of the tested PT over the statistical normal PT. The so called normal value for the PT varies a bit depending on the chemistry used for the test and the size and population the nember is based on.
 
A "normal" INR = 1.0 The in INR is a ratio of the tested PT over the statistical normal PT raised to the power of the International Sensitivity Index of the reagents used in the test. The so called normal value for the PT varies a bit depending on the chemistry used for the test and the size and population the nember is based on.

The most sentitive ISI is 1.0. So the less sensitive the material will have a higher exponent. Therefore, the further the INR varies from 1.0 the less accurate the number will be. Ah, but that does not answer the question, "What is normal".

You must climb the highest mountain and seek the guru to find out, "what is normal".
 
allodwick said:
You must climb the highest mountain and seek the guru to find out, "what is normal".
Is that like the scene in this one movie where I forget who has visions of Jim Morrison and a Naked Indian and Jim offers Guru like advice? :confused: :D
 
The NORMAL defined above as 1.0 is for people NOT on Coumadin.

I suspect the original question was in regard to what is the NORMAL RANGE for a patient with a mechanical valve.

THAT NORMAL depends on position (aortic, mitral, etc) and other considerations including individual patient 'symptoms' (indications of clotting such as TIA's or visual effects or hypersensitivity to bruising or bleeding).

Some doc's like 2.0 to 3.0 for single valves in the aortic position. For a valve in the Mitral Position, most doc's seem to favor 2.5 to 3.5 but some like even higher, say 3.0 to 3.5 or 4.0, for patients with clotting risks.

Bottom Line: Ask YOUR cardiologist what range of INR he wants for YOU.

'AL Capshaw'
 
The Professor Al has spoke(n). Thanks Al. It cleared up a few things for me after I read it a couple of times. My brother has been around 4 for some time. They are trying to get it back down by tweaking the med, but it must not be working because we have been going back every 2 wks for re-test. He takes the med to prevent stroke.
 
Ross said:
Is that like the scene in this one movie where I forget who has visions of Jim Morrison and a Naked Indian and Jim offers Guru like advice? :confused: :D
It's Wayne in Wayne's World. Ah, my misspent youth!
 
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