I've slowly been getting to the point where I thought my INR was going to stabilize. I've been working with coumadin clinic nurse & things were going fairly well. 2 weeks ago when I was checked it was 4.6. I was on 5 mg/day. She said hold one dose and continue the 5 mg/day and come back in 2 weeks. I did not hold the dose, but I did appear today at the appointed time. INR today was 1.7. Diet was roughly the same, exercise level was roughly the same, no change in medications. So we modified the dosage again & I'll test next week. I'm not happy about this.