TIA and INR levels

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lance

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What would be the highest INR level a patient would stroke or have a TIA be?

For instance below 1.5 there is a risk, but higher than (fill in the blank) a stroke/TIA would be unlikely.

Any thoughts?
 
Hello! Interesting post.

We have also been told the same thing....unlikely below 1.5 - However, in February, my husband had a TIA when his INR was 1.9 - He has two mechanical valves, and chronic a-fib. I will add that he is also supposed to take an enteric aspirin daily, and had missed two doses. -Marybeth
 
lance said:
What would be the highest INR level a patient would stroke or have a TIA be?

For instance below 1.5 there is a risk, but higher than (fill in the blank) a stroke/TIA would be unlikely.

Any thoughts?

Good Morning Lance....

I had my first Stroke at 2.3....several TIAs with INR levels of 2-3 and my last stroke was at 3.2

Even though my blood was thin....my body still wanted to make alot of platelets...was using a Baby ASA before my last Stroke..but now on a ASA 325...and if I still am having problems...was told to be put on Plavix in addition to Coumadin....
 
LisaD0365 said:
Good Morning Lance....

I had my first Stroke at 2.3....several TIAs with INR levels of 2-3 and my last stroke was at 3.2

Even though my blood was thin....my body still wanted to make alot of platelets...was using a Baby ASA before my last Stroke..but now on a ASA 325...and if I still am having problems...was told to be put on Plavix in addition to Coumadin....

Hi Lisa,

That's a real surprise to stroke at such a high level--3.2. Prior to being anticoagulated you must have been in demand at the local blood bank for donating to hemophiliacs.

Cheers
 
lance said:
What would be the highest INR level a patient would stroke or have a TIA be?

For instance below 1.5 there is a risk, but higher than (fill in the blank) a stroke/TIA would be unlikely.

Any thoughts?


First of all, the coumadin reduces the risk rather than eliminates it. The risk is increased with anything below your range. I was diagnosed as having had an embolic event (mitral valve threw a clot ) and my INR was 4.0 in the ER. It was still within the first several months after my surgery and perhaps the clot developed when my INR was a little lower but impossible to determine. I too have periods of atrial fib and that increases the risk.

I think I have read that after about 4.0 there is little additional protection by increasing coumadin.

Last week I had my routine cardiology appt. It was brief and to the point. Talking points: 1.Keep INR up; 2. Stay out of atrial fib; 3. Exercise more.
 
It's the lower INRs that have the possibility of causing TIAs. When Joe's goes to 1.9 or so, he is in his danger zone.

But prior to having his mitral fixed up, he was having TIAs "in range" which for him is 2.5-3.5.
 
I use a lot of driving analogies. The speed you are actually traveling corresponds to the INR. For this getting hit from behind is a stroke or TIA. If you are going 15 on 75 speed limit interstate the risk is high. If you are doing 90, the risk is less but it is not a guarantee than it won't happen.

Also the longer you try to stay at that speed, the greater the likelihood of an adverse event.

This is why I believe that any INR more than 0.2 units below the range needs to have action. And why I do not believe that an INR 0.3 units above the range requires action. It is easier to stop a nosebleed than to inplant another valve.
 
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