I'm going sing my refrain again about drug information:
Go to your pharmacist first. My experience has been that doctors and their staffs, including cardiologists, are generally not thoroughly knowledgeable about drugs insofar as their side effects and interactions. Yes, discuss with your doctor, but understand that drugs and interactions are a pharmacist's specialty, not a doctor's. Go to your doctor armed with the information you get from your pharmacist, and you will be able to participate in the discussion, instead of just listening and nodding your head dubiously.
CoQ10 is ubiquitous in the body, but adding CoQ10 from external sources is not synonymous with having it created from within. Here are some thoughts about how taking an external source of CoQ10 may affect you...
CoQ10 lowers INR for warfarin/Coumadin users. You can dose the diet, but you should be aware of the effect, especially when you first start taking it.
Pegasus mentioned the issue with combining CoQ10 supplementation with some blood pressure medications: it can enhance their effectiveness unexpectedly, making you liable to dizziness or fainting.
As far as its interactions with beta blockers (such as Atenolol or Metroprolol) and statins (such as Lipitor or Zocor): both beta blockers and statins perform part of their work by slowing down or interfering with some chemical interactions that CoQ10 assists. Sometimes this results in lower bodily CoQ10 levels (especially with statins). The question in play is whether it helps to add more CoQ10 and boost the body's level back up, or whether adding CoQ10 interferes with the actions of the drugs.
Even the Mayo Clinic cites a likelihood that CoQ10 can cause "small decreases in blood pressure." However, there is a caveat to using that statement as a generalized proclamation, inthat it is a
small decrease, and the studies indicate it does so primarily
in people who have a CoQ10 deficit, similar to its benefits to those with heart failure and low CoQ10 levels. There far less evidence that it has any effect on people who have normal levels of CoQ10.
As far as other claims, Mayo doesn't seem to find the science compelling at this time.
http://www.mayoclinic.com/health/coenzyme-q10/NS_patient-coenzymeq10
Levels of CoQ10 in the body can be increased by taking CoQ10 supplements, although it is not clear that replacing "low CoQ10" is beneficial. CoQ10 has been used, recommended, or studied for numerous conditions, but remains controversial as a treatment in many areas.
The other thing about CoQ10 that you should remain aware of: like many chemical compounds manufactured by the body, its levels are also regulated by the body. When levels are being supplemented from the outside, internal production slacks off to an extent. Studies have shown that a period of low CoQ10 levels results when people stop taking CoQ10 suddenly, before the body adjusts and begins to manufacture the dirrerence again. So if you're going on vacation, you should bring it with you. If you're fickle about medications, consider if this is a good supplement for you.
Thank you,