prilosec OTC rebate

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Good to know.

For the few here who may take Plavix: Plavix doesn't go well with Prilosec or other proton-pump inhibitors. These include: omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), esomeprazole (Nexium), and Zegarid. They use the same chemical route to exit the body, and there's not enough of the chemical to let them both out through the liver at the proper rate. Talk to your doctor if you are on Plavix and want to use serious antacids.

Also be aware that these acid reducers can increase the concentration of digoxin (Lanoxin) in the blood and can increase INR (especially Prilosec) for those using warfarin. Those on digoxin should discuss the use of any of these with their doctors or pharmacists. Those on warfarin would just monitor and adjust for it, if needed.

There are also side effects from these drugs with long-term or nearly continuous use. That's what's obviously being pushed here, despite the instructions on the package about only using them for very limited periods of time (14 days at a time, up to three times per year). Based on the instructions for OTC use, one 42-count box of Prilosec is a year's supply - but you must buy two for the rebate.

The FDA has issued warnings for long-term use (over a year) or higher dosages of Proton Pump inhibitors for increased danger of fractures of the spine, hip, and wrist, and possible increased rate of infection by clostridium difficile, a bacterium that is hard to get rid of and causes severe diarrhea.

It's tough to stop taking them after 14 days, because they work so well (I use them, too). However, as with any drug, you should get up-to-date on their evil side, so you know what to keep an eye out for. The fact that some of them are now being sold OTC (over the counter) doesn't make any of them less serious drugs or their possible ill effects any less.

Best wishes,
 
Bob -- My internist has prescribed Prilosec for long-term use (excess acid production, leads to acid reflux, etc.). If I wanted to follow the manufacturer's instructions, how would I dose? Would I use the med for the two weeks, then take "a break" from it? How long?

I agree that these meds work wonders for some of us, just looking for the best way to use it.
 
Bob -- My internist has prescribed Prilosec for long-term use (excess acid production, leads to acid reflux, etc.). If I wanted to follow the manufacturer's instructions, how would I dose? Would I use the med for the two weeks, then take "a break" from it? How long?

I agree that these meds work wonders for some of us, just looking for the best way to use it.

my doctor presrcibed me for long term too. IF I stop I get pretty bad heart burn in just a couple days. the directions frm prilosec's site are
Adults 18 years of age and older
This product is to be used once a day (every 24 hours), every day for 14 days
It may take 1 to 4 days for full effect, although some people get complete relief of symptoms within 24 hours

14-Day Course of Treatment
Swallow 1 tablet with a glass of water before eating in the morning
Take every day for 14 days
Do not take more than 1 tablet a day
Do not chew or crush the tablets
Do not crush tablets in food
Do not use for more than 14 days unless directed by your doctor


Repeat 14-Day Courses (if needed)
You may repeat a 14-day course every 4 months
Do not take for more than 14 days or more often than every 4 months unless directed by a doctor

here is a link to the NIH page http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000936#a693050-how
 
my doctor presrcibed me for long term too. IF I stop I get pretty bad heart burn in just a couple days.

Same here. And, I can't stand that pain..... :(



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They say that's the drawback of long-term use -- the rebound effect whenever we stop it. . .

Not sure what I'll end up doing when I go into the hospital for surgery. Maybe they will continue the Prilosec, maybe not. Can't worry about it, I guess.
 
Duff Man - I also had wierd reactions to Prilosec the first time I tried it. Really wild anxiety attacks. Switched to Zantac for a month - didn't work as well. Switched back to Prilosec, no problem. Go figure. . .
 
Duff Man - I also had wierd reactions to Prilosec the first time I tried it. Really wild anxiety attacks. Switched to Zantac for a month - didn't work as well. Switched back to Prilosec, no problem. Go figure. . .

I think you're one of the only people I've heard of that've had a reaction like me. I get anxiety AND major league depression. Like, suicidal ideation within 6 hours of taking a PPI. It's very strongly correlated and it's usually about the same reaction.

One time a nurse accidentally gave me protonix after reading my chart's allergy list and (for whatever reason) thinking it was my medication list... she injected it via IV without me knowing. I was wigging out right afterward but I had no idea why. Finally I asked for Zantac and my beta blocker and she said she'd already given me "my" PROTONIX iv!! I had to explain to the woman that it's an allergy not a regular medication, and I needed some kind of anxiolytic or benadryl or something. After a nice push of Ativan I felt kind of satisfied because I finally had a blinded test that confirmed I really do have the weird reaction despite the doc's doubts, but I was pissed because I was freaking out sooooo bad and it could've been worse.
 
Duff Man - I got the same reaction from my internist. He didn't want to believe me that I had the anxiety attacks from Prilosec, even though I told him that the attacks stopped within 24 hours of cessation of the Prilosec. He then told me to "Take any of the over-the-counter acid preventers. Any of them will do the job we need done."

He will be even more doubtful when I tell him that after a month or so on Zantac I switched back to Prilosec with no ill effects.
 

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