Premarin

[BTMax]

I just recently quit taking Premarin--my GYN was very definite that I should not take it with Coumadin. My heart sugeon knew I was taking it and never said to stop it and my cardiologist has never told me to stop it. I am miserable without it---hot flashes, etc and terminal grouchiness --my poor husband. He really wants this info more that I do! Any info from your experiences will be appreciated. Thank you

 

[geebee]

I chose not to go on HRT after discussions with my doctors. There is too much association with strokes & heart disease to say nothing of breast cancer recurrence. Even though I am on coumadin and probably protected from stroke, the other risks were not worth it.

I have had my moments with hot flashes and mood swings but I am happy to say I am still alive to experience them. That knowledge is what gets me through.

I took soy supplements for a few years and I think that got me through the worse. The supplements did affect my INR but it was quickly adjusted. You might want to try some soy.

 

[tobagotwo]

The usual issue with those drugs is that they can increase the likelihood of strokes. If you're on Coumadin, that risk is largely mitigated.

I would check some more, including with pharmacists, and check Al Lodwick's site. I don't have the facts in front of me, but my gut feel is your gynecologist is off course.

Note that I'm not much in favor of this type of drug therapy for any length of time, but would feel remiss if I didn't point out what appears to be a logical flaw.

Best wishes,

 

[geebee]

http://www.holistic-online.com/Remedies/hrt/hrt_hrt_risks-of-ERT.htm

 

[barbwil]

30 years

30 years

I've been taking Premarin since my hysterectomy and oopherectomy in 1975! After having a kidney out 3 1/2 years ago because of renal cell cancer my PCP suggested that I go off it. I stopped for 2 months and felt like a couple of porcupines were walking up and down my face, neck, and chest. So I am back on it but now take the smallest dose and only every other day, just enough to keep me feeling better. Will it hurt? Who knows?! And I've been on warfarin for those 3 1/2 years.

Barb

 

[Guest]

I think that tobagotwo got it just about right. There is evidence that Premarin increases the risk of clots. It is almost always stopped when someone gets a clot. Warfarin is good at preventing clots. But there are so few reports of people taking warfarin and Premarin that there are no valid conclusions about taking both.

One thought of how Premarin forms clots is that the large amount of estrogen absorbed directly into the liver after swallowing a pill makes the body think that it is pregnant and therefore the liver needs to produce lots of clotting factors to keep a woman from bleeding to death after giving birth. This can probably be prevented by using an estrogen patch. The blood from the skin dilutes throughout the body before getting to the liver. Therefore the liver does not produce lots of clotting factors.

There have been some reports of clots when women used contraceptive patches but it appears that there is an excessive amount of estrogen in these compared to the hormone replacement patches.

 

[BTMax]

Thank you

Thank you

Thank you for all of the info--there's nothing like being able to hear from those who have been there or at least know something about the subject. The patch is an excellent idea. I am going to discuss it with my Dr today! It may save my marriage!

 

[Birky]

premarin

premarin

I was on the patches for nine years but the my PCP took me off 2 years ago. I am still bothered by night sweats but it has gotten better. He thought I should be off due the study about Alzheimers and women that were on hormones. Not sure if I have this right. I have learned to deal with them. I am on Zoloft(I guess kind of a tradeoff) and this works with the mood swings. Good luck,

 

[Christina]

Final Estrogen Report Finds No Heart Disease benefit.

Final Estrogen Report Finds No Heart Disease benefit.

I just recently quit taking Premarin--my GYN was very definite that I should not take it with Coumadin. My heart sugeon knew I was taking it and never said to stop it and my cardiologist has never told me to stop it. I am miserable without it---hot flashes, etc and terminal grouchiness --my poor husband. He really wants this info more that I do! Any info from your experiences will be appreciated. Thank you

This article below was sent to me yesterday by a friend of mine who is a Naturopathic Doctor in Houston.

http://news.yahoo.com/s/usatoday/20060214/ts_usatoday/finalestrogenreportfindsnoheartdiseasebenefit

 

[Christina]

Final Estrogen Report Finds No heart Disease benefit.

Final Estrogen Report Finds No heart Disease benefit.

I've been taking Premarin since my hysterectomy and oopherectomy in 1975! After having a kidney out 3 1/2 years ago because of renal cell cancer my PCP suggested that I go off it. I stopped for 2 months and felt like a couple of porcupines were walking up and down my face, neck, and chest. So I am back on it but now take the smallest dose and only every other day, just enough to keep me feeling better. Will it hurt? Who knows?! And I've been on warfarin for those 3 1/2 years.

Barb

This article below was sent to me yesterday by a friend of mine who is a Naturopathic Doctor in Houston.

http://news.yahoo.com/s/usatoday/20060214/ts_usatoday/finalestrogenreportfindsnoheartdiseasebenefit

 

[sue943]

I was taking Premarin/Prempak for about 20 (yes 20) years as I was having an early menopause and my GPs (two during that time) knowing my family history of heart disease (and no cancer) thought it safer for me to stay on it longterm, at least until most women have their menopause. In June, the day before my surgery, the doctors at the hospital took me off it and I was told that I ought not take it anymore.

The blessing is no more periods! Yes I have hot sweats, but reading these forums it looks as if that could be related to the surgery as some of you men appear to have night sweats.

 

[barbwil]

Christina

Christina

Thank you, interesting article. I would love to see a listing of all the claims and assertions that have been made down through the years, the pros and cons of taking premarin. It's enough to make one dizzy, the rate scientists and physicians have told patients it will save your heart, it will kill you for sure! So in the end we're all going to die and I have enough aches and pains with arthritis, costochronditis, etc. that I'll do whatever gives me some relief, whether it be for 1 mo. or 25 yr. and hope to leave this world with a smile on my face and praise in my heart!

God bless, Barb

Know any man who has been given estrogen for prostate cancer? Now you're talking "night sweats"!

 

[Guest]

I remember a speaker back in the 1980s saying that a woman should start on birth control pills wher her period starts and when it stops she should takes estrogens for the rest of her life. Through much of the 80s and 90s Premarin was the best selling drug in the US.

Trying to find a generic for Premarin was the quest for the Holy Grail of generics. Wyeth had a fleet of lawyers that seemed as big as its sales force trying to keep the generic off the market. They were largely successful.

You know that the name came from PREgnant MAre's urINe!!! It was a fully natural product which is why nobody could develop a synthetic that had all of the trace ingredients of horse pee. The battle to hold off generics hinged on that one small fact. Personally, I always wanted to see the herd of pregnant mares!!

BTW - one of my colleagues whose last name is Dwyer has a wife whose first name is Barbara. Guess what her name plate on her desk is?

 

[barbwil]

I'll bite....

I'll bite....

BTW - one of my colleagues whose last name is Dwyer has a wife whose first name is Barbara. Guess what her name plate on her desk is?
__________________
I must need to get off and go to bed 'cause I don't get it, Al.

 

[geebee]

BTW - one of my colleagues whose last name is Dwyer has a wife whose first name is Barbara. Guess what her name plate on her desk is?
__________________
I must need to get off and go to bed 'cause I don't get it, Al.

I think he means Barb Dwyer (barbed wire).

 

[barbwil]

Dah!!!

Dah!!!

I think he means Barb Dwyer (barbed wire).

Thanks, Gina. I woke up this morning thinking "Barbara Dwyer", "Barbara Dwyer"; I just didn't get it! How dumb is that? And to think I call myself Barb all the time! May I claim "pumphead"?

 

[lance]

I remember a speaker back in the 1980s saying that a woman should start on birth control pills wher her period starts and when it stops she should takes estrogens for the rest of her life. Through much of the 80s and 90s Premarin was the best selling drug in the US.

Trying to find a generic for Premarin was the quest for the Holy Grail of generics. Wyeth had a fleet of lawyers that seemed as big as its sales force trying to keep the generic off the market. They were largely successful.

You know that the name came from PREgnant MAre's urINe!!! It was a fully natural product which is why nobody could develop a synthetic that had all of the trace ingredients of horse pee. The battle to hold off generics hinged on that one small fact. Personally, I always wanted to see the herd of pregnant mares!!

BTW - one of my colleagues whose last name is Dwyer has a wife whose first name is Barbara. Guess what her name plate on her desk is?

Al, Are you really sure you want to see see the herds of pregnant mares all hooked up to their collection bags?

 

[geebee]

Thanks, Gina. I woke up this morning thinking "Barbara Dwyer", "Barbara Dwyer"; I just didn't get it! How dumb is that? And to think I call myself Barb all the time! May I claim "pumphead"?

Honey,
You can claim anything you want. Once I reached 50 AND had 3 OHS behind me, I figured I can claim pumphead, senior moments, and brain farts, all depending on the situation.
I can explain away almost everything.