psalmist
Well-known member
Okay, I had an ear infection and I am on 10 days of antibiotics 1 pill every 8 hours of amoxicillan. I home test. I am on my 4th day, do I need to test again? Will increase or decrease my INR. It was 2.8 a week ago.
On Antibiotics
- Thread starter psalmist
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How much amoxi are you taking -- 250 or 500mg?
Amoxi has never affected my INR. I take it for dentals and when I get bitten or scratched (badly) by a cat. When I get bitten or scratched, I take 2,000mg immediately, then contiinue with 500-1,000mg every 6-8 hours for about 2 days. Never had any affect on my INR.
Amoxi has never affected my INR. I take it for dentals and when I get bitten or scratched (badly) by a cat. When I get bitten or scratched, I take 2,000mg immediately, then contiinue with 500-1,000mg every 6-8 hours for about 2 days. Never had any affect on my INR.
Seth, 10 days is alot of antibs, if it was me, I would test again this week.
psalmist
Well-known member
Great!
Great!
I wasn't sure. I just want to be extra careful when it comes to that stuff.
Great!
I wasn't sure. I just want to be extra careful when it comes to that stuff.
Me too....I think that my peace of mind is worth a 7 dollar test strip. 
Seth, I have been on amox. many times, usually prior to dental appointments. Never had a problem with INR going up or down. If you test weekly, I'd test at the normal time. Since you will be on the antibiotic for many days, it might require some warfarin adjustment. But, then again, it may have no effect at all.
Check out:
http://www.hemosense.com/docs/5500331_TechBull110_DrugInteractRevA.pdf
Does not appear that amoxi will affect the INR, at least not enough to worry about.
There's a French study underway on INR & amoxicillin-clavulanic acid (I think that's Augmentin; I know it as Clavamox in veterinary medicine):
The aim of the present study is to determine if AM-CLAVAC can increase the pharmacodynamics of warfarin among patients at steady state Double blinded cross over controlled study vs placebo performed in 12 evaluable patients treated with warfarin with an INR target 2 to 3 and a stable INR and a stable dose.
http://www.druglib.com/trial/17/NCT00603317.html
http://www.hemosense.com/docs/5500331_TechBull110_DrugInteractRevA.pdf
Does not appear that amoxi will affect the INR, at least not enough to worry about.
There's a French study underway on INR & amoxicillin-clavulanic acid (I think that's Augmentin; I know it as Clavamox in veterinary medicine):
The aim of the present study is to determine if AM-CLAVAC can increase the pharmacodynamics of warfarin among patients at steady state Double blinded cross over controlled study vs placebo performed in 12 evaluable patients treated with warfarin with an INR target 2 to 3 and a stable INR and a stable dose.
http://www.druglib.com/trial/17/NCT00603317.html
L
Lisa in Katy
I would test after you've been on it about a week just to make sure. Antibiotics are just weird. The same one may raise, lower, or do nothing to the INR, depending on the person. The only antibiotic I've ever taken that did nothing is Clindamycin.
BDMc
Well-known member
Hey Seth! Sorry about the infection. They suck. I've never had a problem with amox. but think Lisa's advice is good just to set yourself at ease, and be sure you don't need an adjustment while your on it. Hope you are feeling better. Brian
