Medications and CHF and/or kidney failure

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Nancy

Well-known member
Joined
Jun 9, 2001
Messages
9,896
Location
upstate New York
Just wanted to mention something for those with CHF who also might have intermittant kidney failure.

Joe has had a couple of serious consequences with some of his medications which were either prescribed incorrectly for his conditions or built up in his system, causing strange symptoms.

The first med was Paxil. Although his dose was long standing, and well tolerated, once his CHF and kidney failure got to a certain level with ascities, it built up in his system and caused palsy-like problems including shaking hands, slow gaited walking, unsteadiness, and slow thinking. It took some sleuthing and many lab tests to rule out everything else. His dose was cut in half and things got a lot better, and he is still OK, depression-wise.

Another just happened recently. He went to a new and young doctor for his voice problems (ENT). She prescribed Zantac in a very large dose, 300mg. He immediately started getting headaches, felt blah and listless and his CHF worsened. We weren't sure what was going on, and had to call his card. and his hematologist and his labs turned out just fine anemia-wise and cardio-wise.

The symptoms started to happen with the beginning of the whopping Zantac dose, so he stopped taking it, however, his CHF has still been a problem, in spite of Lasix, Aldactone and even Zaroxolyn.

A little more sleuthing with the help of the card's NP and the teaching hospital's pharmacist, turned up the fact that 300mg was way too much for anyone with compromised kidneys, and Joe should have been started on a much, much lower dose to see how things went and should have never exceeded 150mg. He probably shouldn't have been given it at all.

It turns out that Zantac can cause renal interference and liver problems, and a blah feeling and headaches.

There are "renal doses" for those who have the potential for kidney problems and Joe should have been on the renal doses.

The other unfortunate thing is that because Zantac is excreted in the kidneys and metabolized in the liver, it will hang around longer in Joe's system than it would in an ordinary person's system because his kidneys aren't working 100 percent, so after about a week off it, he still has symptoms.

So another lesson learned the hard way.

When you are getting a new prescription and you have CHF and/or kidney problems, ask the doctor if it has to be adjusted for your personal problems. Not every doctor thinks about that. There are also dose adjustments for renal and older folks too. And you may need a much lower dose at least to start.
 
Thanks For The Info Nancy!!!

Thanks For The Info Nancy!!!

Thank God I am not on either of those meds, and I will stay away from them, as I definitely do not need my CHF acting up at this point. Thanks again. Harrybaby :D :eek: :D
 
Nancy,
I seriously believe a valve Forum should be dedicated to the vast amount of knowledge you have accumulated over the years. We could use a search feature dedicated solely to what you've experienced and learned through Joe's trials and tribulations.

Maybe call it, "What Nancy Knows"! :) :) :)
 
Nancy, you should write a book especially for CHF patients! Since my mom had her triple bypass and mitral valve replaced in April, I have learned SO much from your posts. My mom has CHF, kidney problems, etc. and your info has been incredibly helpful. My mom does not have internet access so I just pass along what I read here to her. It amazes me in this day and age how important it is for people to be in control of their own health care-knowledge is power! It is frustrating that medical errors happen (Like the medicine with Joe) Nancy-you are the Nancy Drew of this site and I so appreciate your sharing your knowledge-thank you! :)
 
Joe's a walking talking Merck Manual. It's hard to believe he's been through all the things he's been through. It's not that I know so much as that each piece of information has been learned the hard way when things have gone wrong and it's burned into my brain. So I guess they've gone wrong a lot. :rolleyes: The good news is that he's got several doctors who do things right, and that's why he's still alive. :)

I've also learned so much with all of his appointments. Each one of them is a learning experience. Sometimes, he has 5 medical appointments in one week, plus I'm on the phone with his cardio's NP about once a week.
 
Nancy

Nancy

What you described is a medicine nightmare big time. When a person goes to a new doctor, be sure to question high dosages on new medication and possible reactions and interactions. Most of the people wait till they get to the pharmacy to get information. Ask the doctor then and there. Some doctors overmedicate and that causes major problems. Thank goodness your hubby had you there to help. Hope he is doing better now.
 

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