Hi Nocturne - The article didn't actually say exactly what those people died from. And it wasn't totally clear that the deaths were specifically related to the valve replacement. They could have died in a car accident, died from a respiratory problem, died from a heart attack or stroke related to something other than their valve replacement, died from cancer, and so on. I would have liked to see the figures of causes of death. Certainly saying that a 75 year old having mechanical valve replacement has an average life expectancy of 7 years takes them to average of 82 which is a pretty good innings for anyone, valve replacement or not. And with a 65 year old with tissue valve, average life expectancy 11.3 years, takes them to average age of 76 - simply loads of people die in their 70's, valve replacement or not, from various illnesses unfortunately. The average life expectancy of the 35 year old with mech valve of only 16 to 22 years is a surprise, but again I'd like to know exactly what they died from. What a person can do with statistics.