Some stringers regarding heart health pulled from larger, sometimes intensely boring documents found on the web...
-- The FDA is now allowing a qualified health claim for a reduced risk of coronary heart disease on foods that contain omega-3 fatty acids (EPA and DHA). This is noteworthy, as compound(s) have to prove that they are significantly effective to be allowed to make health benefit claims.
This would include oily kinds of fish, such as salmon, trout, tuna, and herring. Scientific evidence suggests they may be beneficial in reducing CHD, according to the FDA statement. http://www.fda.gov/bbs/topics/news/2004/NEW01115.html
-- As long as a year ago, studies had begun showing that omega-3 fatty acids also have an anti-arrhythmic effect on people with atrial fibrillation. http://www.circulationaha.org More recent studies have also shared this outcome with two grams daily of omega-3-bearing fish oil supplements.
-- Some herbs to watch out for with warfarin: "...Chamomile, licorice root, quassia, and red clover all contain either coumarin or coumarin derivatives. [intensify warfarin - RDH]
"Further, licorice root contains glycyrrhetinic acid which can increase blood pressure.
"Meadowsweet, poplar, and willow bark all contain salicylates. [aspirin-related compounds that have an antiplatelet effect, increasing bleeding risk - RDH]"
Some Siberian Ginseng supplements may also contain traces of Chinese Silk Vine, which can multuiply the effects of digoxin. http://www.theheart.org/viewArticle.do?simpleName=218618
Fri, 18 Aug 2000 16:48:52 Pippa Wysong
-- More interactions:
"Ma huag. Contains ephedrine.
Foxglove. A source of digitalis.
Hawthorn. It contains oligomeric procyanins, and has hypocholesterolemic action. [increases effect of anticholesterol medications - RDH] This herbal can increase coronary blood flow and enhance the activity of digoxin.
Dan-shen. This Chinese sage and root has possible vasodilatory action [relaxes blood vessels - RDH], may inhibit platelet aggregation [same effect as aspirin, Plavix - RDH], and has a protective action on ischemic myocardium. It may potentiate [increase - RDH] warfarin's side effects, however.
Willow bark. Contains salicin (a source of ASA). [same effect as aspirin, Plavix - RDH]
Garlic. Has demonstrated antiplatelet activity, and high doses may reduce serum thromboxane levels. [same effect as aspirin, Plavix, and additional anticlotting action - RDH]
Ginko (maidenhair tree). Ginkolides inhibit platelet-activating factor, decrease vascular resistance, and improve circulatory flow.
Hellebore. Contains alkaloids that may cause vomiting, bradycardia, hypotension
Wu-chu-u (Evodia rutaecarpa). Contains rutaecarpine, a vasorelaxant."
From Herbs: Everyday Reference for Health Professionals. Frank Chandler, editor-in-chief. Canadian Pharmacists Association and Canadian Medical Association, publishers.
-- Still more interactions:
Anise and dong quai have anticoagulant effects.
Omega-3 fatty acids in fish oil, garlic, ginger, ginkgo, and vitamin E all have antiplatelet properties.
St John's wort and American ginseng affect drug metabolism.
From: NIH conference focuses on effects of dietary supplements on antithrombotics Jan 20, 2005 Susan Jeffrey http://www.theheart.org/viewArticle.do?primaryKey=382707&from=/searchLayout.do
-- Statin Woes: A new study by "Dr Robert Wortmann (University of Oklahoma College of Medicine, Tulsa) reported that...patients who developed statin myopathies...are 11 times more likely to be heterozygous carriers for carnitine palmitoyltransferase (CPT) II deficiency and 20 times more likely to be carriers for McArdle's disease (glycogen storage disease Type V) and have 4 times the usual rate of myoadenylate deaminase deficiency."
All of these are genetic muscle disorders. In order to have statin issues, it wasn't necessary to have the muscular problems, it was sufficient just to be a carrier of the gene set. Most people with problems had lower levels than normal of Coenzyme Q10. Treatments suggested were adding COQ10 and Carnitine supplements for patients with problems. From Genetic risk factors for statin myopathy found; coenzyme Q10, carnitine supplements might help Oct 22, 2004 Janis Kelly http://www.theheart.org/viewArticle.do?primaryKey=326053
-- Economy-class syndrome Guideline recommendations for long flights were made this January, as more information on the topic has become available recently.
"The risks are small and almost entirely limited to people with other risk factors for venous thrombosisthose with previous venous thrombosis, thrombophilia, chronic illness," according to Dr. Jack Hirsh. Recommendations are the use of self-administered Low Molecular Weight Heparin and the use of compression stockings are effective. One other study of aspirin suggested it is not effective. For the average person, though, doing isometric muscle contractions and keeping well hydrated is probably sufficient.
From: New thrombosis guidelines from the American College of Chest Physicians Wed, 15 Sep 2004 21:30:00 Susan Jeffrey http://www.theheart.org/viewArticle.do?primaryKey=159063&from=/searchLayout.do
Best wishes,
-- The FDA is now allowing a qualified health claim for a reduced risk of coronary heart disease on foods that contain omega-3 fatty acids (EPA and DHA). This is noteworthy, as compound(s) have to prove that they are significantly effective to be allowed to make health benefit claims.
This would include oily kinds of fish, such as salmon, trout, tuna, and herring. Scientific evidence suggests they may be beneficial in reducing CHD, according to the FDA statement. http://www.fda.gov/bbs/topics/news/2004/NEW01115.html
-- As long as a year ago, studies had begun showing that omega-3 fatty acids also have an anti-arrhythmic effect on people with atrial fibrillation. http://www.circulationaha.org More recent studies have also shared this outcome with two grams daily of omega-3-bearing fish oil supplements.
-- Some herbs to watch out for with warfarin: "...Chamomile, licorice root, quassia, and red clover all contain either coumarin or coumarin derivatives. [intensify warfarin - RDH]
"Further, licorice root contains glycyrrhetinic acid which can increase blood pressure.
"Meadowsweet, poplar, and willow bark all contain salicylates. [aspirin-related compounds that have an antiplatelet effect, increasing bleeding risk - RDH]"
Some Siberian Ginseng supplements may also contain traces of Chinese Silk Vine, which can multuiply the effects of digoxin. http://www.theheart.org/viewArticle.do?simpleName=218618
Fri, 18 Aug 2000 16:48:52 Pippa Wysong
-- More interactions:
"Ma huag. Contains ephedrine.
Foxglove. A source of digitalis.
Hawthorn. It contains oligomeric procyanins, and has hypocholesterolemic action. [increases effect of anticholesterol medications - RDH] This herbal can increase coronary blood flow and enhance the activity of digoxin.
Dan-shen. This Chinese sage and root has possible vasodilatory action [relaxes blood vessels - RDH], may inhibit platelet aggregation [same effect as aspirin, Plavix - RDH], and has a protective action on ischemic myocardium. It may potentiate [increase - RDH] warfarin's side effects, however.
Willow bark. Contains salicin (a source of ASA). [same effect as aspirin, Plavix - RDH]
Garlic. Has demonstrated antiplatelet activity, and high doses may reduce serum thromboxane levels. [same effect as aspirin, Plavix, and additional anticlotting action - RDH]
Ginko (maidenhair tree). Ginkolides inhibit platelet-activating factor, decrease vascular resistance, and improve circulatory flow.
Hellebore. Contains alkaloids that may cause vomiting, bradycardia, hypotension
Wu-chu-u (Evodia rutaecarpa). Contains rutaecarpine, a vasorelaxant."
From Herbs: Everyday Reference for Health Professionals. Frank Chandler, editor-in-chief. Canadian Pharmacists Association and Canadian Medical Association, publishers.
-- Still more interactions:
Anise and dong quai have anticoagulant effects.
Omega-3 fatty acids in fish oil, garlic, ginger, ginkgo, and vitamin E all have antiplatelet properties.
St John's wort and American ginseng affect drug metabolism.
From: NIH conference focuses on effects of dietary supplements on antithrombotics Jan 20, 2005 Susan Jeffrey http://www.theheart.org/viewArticle.do?primaryKey=382707&from=/searchLayout.do
-- Statin Woes: A new study by "Dr Robert Wortmann (University of Oklahoma College of Medicine, Tulsa) reported that...patients who developed statin myopathies...are 11 times more likely to be heterozygous carriers for carnitine palmitoyltransferase (CPT) II deficiency and 20 times more likely to be carriers for McArdle's disease (glycogen storage disease Type V) and have 4 times the usual rate of myoadenylate deaminase deficiency."
All of these are genetic muscle disorders. In order to have statin issues, it wasn't necessary to have the muscular problems, it was sufficient just to be a carrier of the gene set. Most people with problems had lower levels than normal of Coenzyme Q10. Treatments suggested were adding COQ10 and Carnitine supplements for patients with problems. From Genetic risk factors for statin myopathy found; coenzyme Q10, carnitine supplements might help Oct 22, 2004 Janis Kelly http://www.theheart.org/viewArticle.do?primaryKey=326053
-- Economy-class syndrome Guideline recommendations for long flights were made this January, as more information on the topic has become available recently.
"The risks are small and almost entirely limited to people with other risk factors for venous thrombosisthose with previous venous thrombosis, thrombophilia, chronic illness," according to Dr. Jack Hirsh. Recommendations are the use of self-administered Low Molecular Weight Heparin and the use of compression stockings are effective. One other study of aspirin suggested it is not effective. For the average person, though, doing isometric muscle contractions and keeping well hydrated is probably sufficient.
From: New thrombosis guidelines from the American College of Chest Physicians Wed, 15 Sep 2004 21:30:00 Susan Jeffrey http://www.theheart.org/viewArticle.do?primaryKey=159063&from=/searchLayout.do
Best wishes,
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