I read in Reader's Digest and a couple of other articles about the gene that causes slow metabolizing of warfarin. Does anyone (maybe Al) know anything about it. Did anyone else read the article. I seem to be a slow metabolizer. Maybe there will eventually be more testing sites. I wonder if it is worth it to travel that far to get tested. I think it is called pharmacogenomics, meaning personalized medicine. The variation of the gene associated with warfarin metabolism is called 2C9. The article says that testing patients could reduce the number of overdoses from 16 percent to 6.5 percent. Wonder if all this is true.
Genotyping for warfarin
- Thread starter Missy
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Ross
Well-known member
Honestly, I think the solution is to educate the people doing the dosing. There are far too many that haven't got a clue what they are doing and that's downright scary if not just plain dangerous.
If you were being tested by someone who knows whats going on and knows what to do, there shouldn't be any overdosing or underdosing no matter what.
I'm interested in Al's reply on this one.
If you were being tested by someone who knows whats going on and knows what to do, there shouldn't be any overdosing or underdosing no matter what.
I'm interested in Al's reply on this one.
Z
Zipper
Right on Ross
Right on Ross
I have been on coumadin for 6 years now....other than the initial adjustment after surgery, I have educated myself thru this and other sites. Al gives the absolute solutions to the problems that most providers do not even understand. I home test/adjust my own doseage, if necessary, and also visit the lab once a month to verify the accuracy of my protime (only because my insurance wouldn't pay for home testing but DOES pay the lab). I have followed Al's educated info and keep my INR in range on a consistant basis. I do not think most providers are as helpful or informative as Al. He is, after all, an expert and I trust his advice to keep my INR level. It's worked for 6 years for me. Thanks Al for all you do...you're a blessing to us all!
zipper *~*
Right on Ross
I have been on coumadin for 6 years now....other than the initial adjustment after surgery, I have educated myself thru this and other sites. Al gives the absolute solutions to the problems that most providers do not even understand. I home test/adjust my own doseage, if necessary, and also visit the lab once a month to verify the accuracy of my protime (only because my insurance wouldn't pay for home testing but DOES pay the lab). I have followed Al's educated info and keep my INR in range on a consistant basis. I do not think most providers are as helpful or informative as Al. He is, after all, an expert and I trust his advice to keep my INR level. It's worked for 6 years for me. Thanks Al for all you do...you're a blessing to us all!
zipper *~*
G
Guest
Well I'm set up to be shot down now!!
The genetic testing is an interesting new development. Brian Gage is a physician at Washington U Medical School in St. Louis. We have been friends for several years. He is one of the leading researchers in putting this into practice. I am planning to go to a meeting where he is speaking at Whisler BC in July.
Tough life- Vail in June; Whisler in July.
The genetic testing is an interesting new development. Brian Gage is a physician at Washington U Medical School in St. Louis. We have been friends for several years. He is one of the leading researchers in putting this into practice. I am planning to go to a meeting where he is speaking at Whisler BC in July.
Tough life- Vail in June; Whisler in July.
Al, would you let us all know your opinion after you attend?
G
Guest
I've never been accused of keeping my opinions bottled up inside me.
Al:
Will be interested in hearing what you think.
BTW, please package some of that sure-to-be-cool air in BC and ship it down here to Texas. I'll be in Nawlins July 9-11 and I'm sure it'll be like a sauna then......
Will be interested in hearing what you think.
BTW, please package some of that sure-to-be-cool air in BC and ship it down here to Texas. I'll be in Nawlins July 9-11 and I'm sure it'll be like a sauna then......
