First Adjustment in Years

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Lisa in Katy

After quite a while on the same dose (maybe 4+ years, although I don't remember), I'm having to adjust. My INR was 2.4 last month, which I wasn't comfortable with, but still in range. My range is 2.5-3.5, but 0.1 off is okay. I just don't like the low side. I actually self-adjusted then because I was taking 7 mg 6 days and 6 mg 1 day, so I started taking 7 mg each day, adding only 1 mg per week, which I didn't expect to make much difference, but perhaps give me a small boost. However, yesterday it was 1.9, which is obviously out of range. I'm waiting for the nurse to call me back. I figure a 10% increase would put me at about 7.7 mg. Since Warfarin comes in 7.5's, I'm thinking that's where I'll be.

Nothing has changed dramatically in my diet/exercise program. The only thing I can think of is at 46, I could be going through menopause, and hormone changes can affect the INR since everything else does. Since I had a partial hysterectomy 8 years ago, I would have to experience other symptoms that indicate menopause is beginning. I'm not having any (I'm always bitchy, so nothing new!), but my mom never had hot flashes or any other symptoms either, just slowed and eventually stopped having a period.

I just hope this can be solved easily and I don't have to go on the INR merry-go-round. I get motion sick!
 
Tread carefully dear Lisa. You may have the right idea and something else may be going on temporarily that you can't control. Mines done that a couple times now over 6 years. For 2.4, I would not increase more then 5% total over the week. Long story short---I made a couple %5 adjustments and suddenly whatever the problem was cleared and I ended up at 5.3.
 
It was 2.4 last month and 1.9 this month, so seems to be in decline. I adjusted about 2% for the 2.4, but it still went down. Other than hormones, can anyone thing of anything else?
 
The only time in nearly 7 years that my husbands INR went low and we could not figure out why was because he started eating a lot of South Beach diet foods and they had a lot of soy in them. Check any new foods you are eating and see if Soy is one of the first few ingredients.
 
I just thought of something. I changed insurance companies on March 1, and had to change labs, so my last two tests were done at LabCorp, and my previous tests were at Quest. I guess this could account for the drop, but the question would be, "Which is correct?"

Any ideas?
 
Well, they decided to put me on 9 mg M, W, F and 7 mg on the rest of the days. Retest in 2 weeks. I'm comfortable with that. I want to be closer to 3.5.
 
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