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Nancy
Well-known member
They lost me here, and I went no further.
Be aware that some patients' genes dictate far lower doses than you usually prescribe, and stay tuned for more precise instructions.
The doctor doses based on what the blood test results are, they don't pull the dose out of the air. No matter what genes a person has, the test results will be the deciding factor in the correct dose.
However, I agree that most doctors need to follow more precise instructions, but apparently not by these people.
Be aware that some patients' genes dictate far lower doses than you usually prescribe, and stay tuned for more precise instructions.
The doctor doses based on what the blood test results are, they don't pull the dose out of the air. No matter what genes a person has, the test results will be the deciding factor in the correct dose.
However, I agree that most doctors need to follow more precise instructions, but apparently not by these people.
ALCapshaw2
Well-known member
It's not as bad as one would think.
They actually got it right about being CONSISTENT with vitamin K intake instead of the old wives tale about NEVER eating anything with Vitamin K.
NBC News had a segment on the story tonight as as you would expect, the message was confusing and distorted when compressed into a short newscast piece.
'AL Capshaw'
They actually got it right about being CONSISTENT with vitamin K intake instead of the old wives tale about NEVER eating anything with Vitamin K.
NBC News had a segment on the story tonight as as you would expect, the message was confusing and distorted when compressed into a short newscast piece.
'AL Capshaw'
Ross
Well-known member
This is exactly why I wish they'd not say anything at all, if what they're going to say is twisted to fit a time slot.ALCapshaw2 said:
G
Guest
I doubt that the FDA is actively seeking a blood thinner.
I think that drug companies are seeking a safe and effective anticoagulant.
I think that drug companies are seeking a safe and effective anticoagulant.
actually I took it to mean they were hoping for a test that would see if people could be on lower doses safely, Lyn
G
Guest
I think that has been pretty well studied and ruled out. If you get more than 0.2 units below your proper range, the effectiveness drops off rather rapidly.
Prior to about 1990 when the INR system was developed many people were kept at pro-times that would correspond to INRs of 8. So todays levels have been adequately studied. It might even be so well proven that these are as low as you can go that studying a lower range would be unethical.
Prior to about 1990 when the INR system was developed many people were kept at pro-times that would correspond to INRs of 8. So todays levels have been adequately studied. It might even be so well proven that these are as low as you can go that studying a lower range would be unethical.
Marty
Well-known member
Each patient needs to find their own dose. On this panel are patients that take 84 mgms/wk and others like me who take 20 mgms/wk. We don't need a fancy genetic test; we need to find our own dose experimentally and then stay with it ,with only minor variations related to diet , exercise, etc.
Natanni
Well-known member
"Stressful Travel " could put Nathan in a danger zone?? So is Nathan's INR going to bonkers when we go on vacation in March? We drive for 24 hours in the car to Galveston....It wil be stressful, no getting around Houston without that.
G
Guest
I use the rule of thumb
Under 65 years old start with 5 mg
Over 65 years old start with 4 mg
Check the INR in 3 to 5 days after starting.
Guess what - the genetic tests predicted that most peopole needed 3 to 6 mg daily. So my rule of thumb worked almost as well as genetic testing. But the people who market the tests will probably wind up convincing everyone that they are a revolutionary breakthrough in medical history.
Under 65 years old start with 5 mg
Over 65 years old start with 4 mg
Check the INR in 3 to 5 days after starting.
Guess what - the genetic tests predicted that most peopole needed 3 to 6 mg daily. So my rule of thumb worked almost as well as genetic testing. But the people who market the tests will probably wind up convincing everyone that they are a revolutionary breakthrough in medical history.
Is this Seattle story the same one that was perhaps on network news Friday?
I've been at a cat show in the Dallas TX area -- judged yesterday, visited today. Close friends mentioned the TV report to me, knowing that I'm on warfarin, but said, "You don't have to worry about that, though. You home-test and know all about warfarin."
(Glad to know that I come across as being very comfortable & confident about taking warfarin.)
I responded that I had seen a post at this website, but no more than that.
I've been at a cat show in the Dallas TX area -- judged yesterday, visited today. Close friends mentioned the TV report to me, knowing that I'm on warfarin, but said, "You don't have to worry about that, though. You home-test and know all about warfarin."
(Glad to know that I come across as being very comfortable & confident about taking warfarin.)
I responded that I had seen a post at this website, but no more than that.
About rivaroxaban (BAY 59-7939):
"Rivaroxaban is a novel, oral, direct Factor Xa inhibitor that reduces the risk of life threatening thromboembolic events. Factor Xa is a protease (the target enzyme) that acts at the pivotal point in the coagulation cascade (the process that leads to clot formation).
Present published results show that rivaroxaban offers predictable anticoagulation across a wide range of parameters, which strongly suggests that coagulation monitoring will not be required."
I hope this new drug can be used for mechanical valve patients, rendering monitoring obsolete yet ensuring relatively safe AC management.
"Rivaroxaban is a novel, oral, direct Factor Xa inhibitor that reduces the risk of life threatening thromboembolic events. Factor Xa is a protease (the target enzyme) that acts at the pivotal point in the coagulation cascade (the process that leads to clot formation).
Present published results show that rivaroxaban offers predictable anticoagulation across a wide range of parameters, which strongly suggests that coagulation monitoring will not be required."
I hope this new drug can be used for mechanical valve patients, rendering monitoring obsolete yet ensuring relatively safe AC management.
