Exanta as of 2/13/2004

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I have done a fairly thorough search of AstraZeneca websites updated in the last month and I can find nothing about Exanta and mechanical heart valves. They have plans listed up through beyond 2006 and this is not on them. I'm wondering if they have given up on seeking approval for use of this drug with mechanical heart valves. There was an article in the Wall Street Journal this week about how the marketing department drives research now. The marketing people may have decided that the chance of a lawsuit settlement, should someone get a clot on Exanta, wiping out any profit potential is too great.

They do say that they have not revealed everything on their website because of the need for competitive advantage so there could be something lurking. However, there are no published reports on the US National Library of Medicine website about even an animal study.

My take is "Don't try to hold your breath until it comes out"

You can read what I wrote at
http://www.warfarinfo.com/ximelagatran.htm
 
This is why I keep telling people that we should be dealing with the "Here and now" and stop trying to predict the future. Too many things, good and bad, can happen between now and later.
 
I just don't see how they will ever be able to do clinical trials for use with mechanical valves. It would almost seem unethical to ask someone to go without their warfarin, wouldn't it?
 
It will be very difficult to do the trials. One group would have to be on warfarin and the other group would be on Exanta. Nobody would be allowed to go without any treatment.
 
New Drug

New Drug

HI Al & Betty
Well, Has anyone heard of a new drug that replace wafarin that is not the that has already be mention here, I am being sent back to my hematologist to try a new medication that has a number the name the cardiologist RN wasn't sure about the name. I go on the 3/16 for visit. They said it would be easier to control. I have a wild two weeks going from .9 to 3.0 but there was lovenox shots and increase of wafarin from 5-12mg. to two shots a day. Have no ideal why it was going crazy. I'll let you all know after I go to the Dr.

SHerrin
Valve repair 5/99
Valve repalcement 3/02
 
I'm sure there are things besides Exanta in development but I don't know abything about them.
 
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