G
Guest
One of our members (RCB) started taking warfarin in 1960. It occurred to me that I went to pharmacy school during that era. I decided to look up what it said about warfarin in my pharmacology book. This is what I learned about warfarin in pharmacy school. Keep in mind that the much-touted leader of the Free World, The President of The United States Dwight Eisenhower was given warfarin in 1955.
Medical Pharmacology: Second Edition copyright 1964 by Andres Goth, M.D. was the textbook that I used in pharmacy school. The chapter on anticoagulant drugs covers ten pages and has nineteen references cited. Of those ten pages, one is devoted to schematics of various chemical structures and one contains the references. This is the entire reference to warfarin:
There is considerable controversy about the usefulness of anticoagulants in diseases of coronary and cerebral vessels. On the other hand, the drugs are considered more useful in thrombophlebitis.
In myocardial infarction favorable results have been claimed,(Footnote#19) but many competent cardiologists now feel that the use of anticoagulants should be reserved for severe cases only.
Many clinical investigators in this country prefer the coumarins and find that warfarin (Coumadin) is one of the best from the standpoint of ease of regulation. It is a good rule for the physician to use the anticoagulant with which he is thoroughly familiar and only if he has facilities for one-stage prothrombin time determinations.
Those 109 words are the total of what many pharmacists, physicians and nurses still practicing today were taught in school. The lone reference footnoted was published in 1954. That was ten years before the book was published.
Medical Pharmacology: Second Edition copyright 1964 by Andres Goth, M.D. was the textbook that I used in pharmacy school. The chapter on anticoagulant drugs covers ten pages and has nineteen references cited. Of those ten pages, one is devoted to schematics of various chemical structures and one contains the references. This is the entire reference to warfarin:
There is considerable controversy about the usefulness of anticoagulants in diseases of coronary and cerebral vessels. On the other hand, the drugs are considered more useful in thrombophlebitis.
In myocardial infarction favorable results have been claimed,(Footnote#19) but many competent cardiologists now feel that the use of anticoagulants should be reserved for severe cases only.
Many clinical investigators in this country prefer the coumarins and find that warfarin (Coumadin) is one of the best from the standpoint of ease of regulation. It is a good rule for the physician to use the anticoagulant with which he is thoroughly familiar and only if he has facilities for one-stage prothrombin time determinations.
Those 109 words are the total of what many pharmacists, physicians and nurses still practicing today were taught in school. The lone reference footnoted was published in 1954. That was ten years before the book was published.
