Inquiring minds want to know: does a mosquito die after biting a person on anticoagulation?
Most folks on this forum are aware that the original use for Warfarin was as a rat poison (and it is still used for that purpose). The rat dies after ingesting Warfarin because when ingested in large quantities it causes internal bleeding.
But what about a mosquito that bites a person on anticoagulation? The mosquito is ingesting a large quantity of blood as a percentage of their body size, and hence a large quantity of Warfarin also. So, does the mosquito suffer internal bleeding and die? See, for example: http://www.youtube.com/watch?v=7V_GBQclQfc
I contacted the American Mosquito Control Association (AMCA) at www.mosquito.org My question to them (by email) is as follows:
Hello, I have to take the anticoagulant medication Warfarin (aka Coumadin) for a heart condition, which is also used as a Rat Poison. When Warfarin is ingested in large amounts, such as by a rat, it causes internal bleeding and the rat dies. I was wondering whether you might know if there have ever been any studies completed, or whether anyone has ever investigated the effect that there might be on a mosquito that bites a person that is on Warfarin? Figuring that a mosquito, by percentage of body weight, would be ingesting a pretty substantial quantity of Warfarin along with the blood that it sucks from a person on Warfarin, there might be a possibility that it would kill the mosquito. I know this probably sounds far-fetched, but I thought it might be worth looking into.
The response I received from Mr. Joseph M. Conlon, Technical Advisor to the American Mosquito Control Association is as follows:
I, too, am on coumadin (7.5 mg/day) as therapy for a pulmonary embolism. Your question is an interesting one. Be advised that the clotting function (that is affected by warfarin) in mosquitoes is of a profoundly different nature than that in mammals and would not be affected by warfarin. Indeed, mosquitoes do not posess blood, per se, but a substance called "haemolymph" which provides turgor and waste transport for the mosquito. Oxygen is taken up by the mosquitoes directly through spiracles and directed to organs via tracheoles.
Highest regards,
Joseph M. Conlon
Technical Advisor
American Mosquito Control Association
P/F: 904-215-3008
Hours: M/W/F 1:00 - 5:00 PM
T/TH 12:00 - 5:00 PM
So, there is the answer. It is not the answer that I wanted to hear, as I was hoping that at least I might be able to get some satisfaction in knowing that the little bastards would die, but such is not the case.
Most folks on this forum are aware that the original use for Warfarin was as a rat poison (and it is still used for that purpose). The rat dies after ingesting Warfarin because when ingested in large quantities it causes internal bleeding.
But what about a mosquito that bites a person on anticoagulation? The mosquito is ingesting a large quantity of blood as a percentage of their body size, and hence a large quantity of Warfarin also. So, does the mosquito suffer internal bleeding and die? See, for example: http://www.youtube.com/watch?v=7V_GBQclQfc
I contacted the American Mosquito Control Association (AMCA) at www.mosquito.org My question to them (by email) is as follows:
Hello, I have to take the anticoagulant medication Warfarin (aka Coumadin) for a heart condition, which is also used as a Rat Poison. When Warfarin is ingested in large amounts, such as by a rat, it causes internal bleeding and the rat dies. I was wondering whether you might know if there have ever been any studies completed, or whether anyone has ever investigated the effect that there might be on a mosquito that bites a person that is on Warfarin? Figuring that a mosquito, by percentage of body weight, would be ingesting a pretty substantial quantity of Warfarin along with the blood that it sucks from a person on Warfarin, there might be a possibility that it would kill the mosquito. I know this probably sounds far-fetched, but I thought it might be worth looking into.
The response I received from Mr. Joseph M. Conlon, Technical Advisor to the American Mosquito Control Association is as follows:
I, too, am on coumadin (7.5 mg/day) as therapy for a pulmonary embolism. Your question is an interesting one. Be advised that the clotting function (that is affected by warfarin) in mosquitoes is of a profoundly different nature than that in mammals and would not be affected by warfarin. Indeed, mosquitoes do not posess blood, per se, but a substance called "haemolymph" which provides turgor and waste transport for the mosquito. Oxygen is taken up by the mosquitoes directly through spiracles and directed to organs via tracheoles.
Highest regards,
Joseph M. Conlon
Technical Advisor
American Mosquito Control Association
P/F: 904-215-3008
Hours: M/W/F 1:00 - 5:00 PM
T/TH 12:00 - 5:00 PM
So, there is the answer. It is not the answer that I wanted to hear, as I was hoping that at least I might be able to get some satisfaction in knowing that the little bastards would die, but such is not the case.
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