Hi
Not that I know of. The usual cause of valve vailure is calcification, which is caused by other metabolic stuff (like immune system ...)
Strain possibly, but I got 20years out of my homograft and it was fitted at about 28 years old.
You may be interested in the results of these studies
done some years back by the hospital that did mine:
The homograft aortic valve: a 29-year, 99.3% follow up of 1,022 valve replacements.
Freedom from reoperation for structural deterioration was very patient age-dependent.
For all cryopreserved valves, at 15 years, the freedom was
- 47% (0-20-year-old patients at operation),
- 85% (21-40 years),
- 81% (41-60 years) and
- 94% (>60 years). Root replacement versus subcoronary implantation reduced the technical causes for reoperation and re-replacement .
also:
Allograft aortic valve replacement: long-term follow-up.
Aortic valve replacement using an allograft aortic valve has been performed on 804 patients.
From December 1969 to May 1975, 124 patients received a nonviable allograft valve sterilized by incubation with low-dose antibiotics and stored for weeks by refrigeration at 4 degrees C (series 1).
From June 1975 to January 1994, 680 patients received viable allograft valves, now cryopreserved early within 2 hours of collection from transplant recipient donors, 6 hours for multiorgan donor valves and 23 hours (mean) for autopsy valves from donor death (series 2).
The probability of a thromboembolic event was low, freedom at 15 years being 95% +/- 1% for patients receiving allografts with or without associated coronary bypass procedures and 81% +/- 5% for patients having allografts with other associated procedures (eg, mitral valve operations). Actuarial freedom from endocarditis was similar for the two series, 91% +/- 3% (series I) and 94% +/- 2% (series II) at 15 years.
The freedom from valve incompetence, from reoperation for all causes, and from structural deterioration demonstrated clearly the inferiority of the 4 degrees C stored allograft valves.
For structural deterioration as identified clinically, at reoperation and at death, freedom from this event at 15 years was
- 45% +/- 6% for series I and
- 80% +/- 5% for series II (p value for the difference is 0).
Hope that helps
