I am out of state for the next few months and away from my doctors. I had a GI bleed and was hospitalized over Christmas while out of state. (Coumadin, Plavix and ASA) In the process, they found that I have Poly Cystic Kidney Disease Stage 3. I saw the local Nephrologist and he mentioned Lisinopril, an Ace Inhibitor, as a blood pressure medication that is used to manage BP in those with Poly Cystic Kidney Disease. I am on Cardizen, a Channel Blocker. I seem to remember that those with mechanical valves should use Channel Blockers? Is this true? I want to ask the local MD to change me over to Lisinopril but would like some opinions on types of BP meds used with mechanical valves. Thanks for any ideas.