I have now been on amiodarone for three months. Here's what I've gleaned from sitting in front of the computer on the net for hours about this drug, talking to pharmacists (including a PM with our own Al Lodwick), two other doctor opinions, etc, etc:
1) Amiodarone should almost never be taken longer than six months. Do everything you can to get off it in six months;
2) Amiodarone frequently shows side effets within two weeks of starting, especially if taking the large dosage required for conversion. If you have no side efects the first two weeks, odds are very good you'll have no side efefects for the rest of the six months (but no guarantee beyond - see #1 above);
3) Once converted, you can stay on a maintenance dosage of 200 mg daily;
4) Yes, you can indeed turn blue, get lung problems and liver problems. However, 85% of all people who take the drug suffer NO side effects;
5) Amiodarone is generally considered the drug of LAST resort for people with "normal" a-fib, i.e., the a-fib is not due directly to an insult to the heart such as open-heart surgery.
6) Amiodarone is sometimes the drug of FIRST resort (depending upon the cardio) when the a-fib is a result of an insult;
7) While on amiodarone, stay very in tuned with your body and have your PCP monitor your blood levels.
8) The half-life of amiodarone is 45 days.
I am not making a recommendation for or against. It appears to be a strong weapon albeit one with potentially devastating side effects. I watch very, very carefully and will be one happy camper when my six months are up. I also have stayed completely out of a-fib since my post-op episode.
Paul