Ann:
Just went to the Alzheimer's Association website and saw this among the theories about the disease:
< Another exciting area of research focuses on the relationship between vascular factors and Alzheimer’s. Researchers have long observed that individuals with known cardiovascular risk factors appear to have an increased risk of developing Alzheimer’s. In addition, recent epidemiological studies suggest that people taking statins, a class of drugs prescribed to lower blood cholesterol levels, may have a lower-than-usual risk of Alzheimer’s. Another study hints that elevated blood levels of the protein building block homocysteine-known to be a risk factor for heart disease-may also increase Alzheimer risk. Further, one form of the gene that codes the cholesterol-carrying protein apolipoprotein E (ApoE), called APOE-ε4, is a known risk factor for late-onset Alzheimer’s. These lines of evidence all support a link between cardiovascular risk factors and Alzheimer’s.
The first clinical trial designed to test the effects of statins is under way as ongoing basic research seeks to clarify the biological links between vascular disease and Alzheimer’s. To encourage such investigations, the Association designated vascular factors in Alzheimer’s as a focus of the 2002 grants program. Confirming and clarifying a vascular/Alzheimer connection raises the exciting possibility that well established strategies for reducing the risk of heart disease-such as exercising, avoiding smoking, and controlling blood pressure and cholesterol levels-may also have value in preventing Alzheimer’s. >
I knew about the theory of amyloid protein deposits as a factor in Alzheimer's. But I had not seen info on any suspected link between cardiovascular factors and Alzheimer's.
Wonder how many people who have had CABG and later were diagnosed with Alzheimer's would have developed Alzheimer's in the absence of any cardiovascular problems?
My mother-in-law died of Alzheimer's at age 64, in 1985. I met her in April 1980, got married in July 1980. Unfortunately, I never knew the "real" Louise.
Doctors ran a battery of tests on her, to rule out carotid blockages. No cardio problems found. She did have thyroid problems.