I've been on spironolactone for literally YEARS and it doesn't bother me.
Spironolactone is a "mild" diuretic that I take in conjunction with furosemide (lasix) to keep the water weight off. The spironolactone doesn't really do much for emptying fluids, but it does a LOT fo helping me retain potassium I would otherwise lose because of the lasix. I've missed doses of spironolactone before and BOY does it make a difference...
Owwie cramps!!!!
There is the pesky brest enlargment issue. I've got pre-pubesant breasts and they can be VERY tender at times, but the trade-off (early on at least) can be massive muscle cramps in my calves that will jolt me out of bed at night, cramps that form a right angle divet in the back of my lower leg. It can be bad all over the place...
I'll stick to the spironolactone thankyouverymuch.
Oh, it increases sun sensitivity too so watch that sunscreen in the summer! I carry a bottle of it with me while I'm out shooting for the paper or out with my family for whatever reason, lather up every two hours or so.
I've had a few knarly burns on odd places like my feet between the straps of my sandals... You can still see a dark patch on my right foot from the first summer I was on the stuff.