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Ross

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Al if you should happen to get a chance, can you highlight us on these new guidelines from Chest?

We've found this:

Finer points: Antithrombotic and Thrombolytic Therapy: ACCP Evidence-Based Clinical Practice Guidelines, 8th edition, has been published as a supplement to the June 2008 Chest. This 900-page document was developed by an international panel of 90 experts and contains the most comprehensive information on the prevention, treatment, and long-term management of thrombotic disorders. For the first time, the guidelines have an entire section (chapter 10) discussing the management of patients on antithrombotic therapy who require surgery. Among the various options, the guidelines discuss the following:

Warfarin therapy may be stopped altogether around 5 days before surgery, instead using subcutaneous low–molecular weight heparin (LMWH) or I.V. unfractionated heparin (UFH) for coverage of high-risk patients. For cost containment, LMWH should be administered on an outpatient basis, with the last dose given 24 hours before surgery.
Antiplatelet therapies such as aspirin or clopidogrel-containing drugs should be stopped 7 to 10 days before the procedure.
Patients undergoing minor dental, dermatologic, or cataract removal should continue to receive warfarin or aspirin therapy.
Patients receiving warfarin who require reversal of the anticoagulant effect for an urgent procedure should be treated with low-dose (2.5 mg to 5.0 mg) I.V. or oral vitamin K.
 
It does sorta say that about stopping warfarin 5 days before a procedure. However, it is only part of a much longer paragraph.

The Chest guidelines draw a distinction between a recommendation and a suggestion. A recommendation is based on very good studies (Grade 1 evidence) while a suggestion is based on less reliable things such as a report of ?what worked for one person?. (Grade 2 evidence)

The recommendation for stopping warfarin for 5 days is followed by? ? In patients with a mechanical heart valve ? at high risk for (clotting) we recommend bridging with therapeutic dose low molecular weight heparin over no bridging ? we suggest LMWH over UFH ( a heparin IV in the hospital) ??

The guidelines continue for several more lines with various lesser clotting risks.

The important thing is that NOWHERE does it say that it is safe for anyone with a mechanical valve to simply discontinue warfarin for any period of time. If anyone?s doctor says otherwise, they are putting you at very high risk for a clot. Abandon that doctor faster than you would a sinking rowboat. It is absolute 100% proof that this doctor is not the least interested in staying up to date. I would love to be the expert witness on the side of the person suing this doctor. I?ll bet that we could reduce anyone who said that to tears!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
 
It aggravates me when they put these things out, then you have to be a paid member to see them or pay to view each chapter. :mad:
 
Sorta true. Chest feels that this is such an important document (it almost carries the same weight as a law) that they make it available without charge, if you don't mind printing 900 pages on your computer. Personally I figured that it was cheaper and quicker to buy it. But a good compromise is to print the 41 page PDF of the executive summary. This can be done at
http://www.chestjournal.org/cgi/reprint/133/6_suppl/71S
 
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