A
Andyrdj
http://www.heart2hearts.co.uk/news008.html
made from the patient's own pericardium during the operation!
made from the patient's own pericardium during the operation!
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Ross
Well-known member
Not that I'm one for studies, but I can't help but wonder how they do at say 10,15,and 25 years. Just something about the word "forever" doesn't seem possible.
Ross said:
I'm not buying into this "valve for life" thing, at least not yet anyways. We see marginal improvements year on year, ultimately leading to acceptable solutions. Like all new methods, let the statistics of this promising new procedure trickle in ...
A
Andyrdj
Long term
Long term
It merits careful reading, the article - hence being in the "new advancements" as opposed to "valve choice"
It seems that there is still a preserving process going on during the operation and that it is still dead, preserved tissue that is being implanted. The estimate was around 20 years for lifetime (which is similar to the estimate for newer Bovine Pericardial Valves).
Now, I'd be interested to know more about the precise mechanism by which such a valve might calcify. The medical wisdom is that calcification is in part a slow, low level rejection process by the body. Would this preserved tissue be immume from this, to some extent? I don't know.
It's possible that the preservative might make the body treat it like any other tissue. In which case, one must ask if there is merit in the process at all. Would a bovine valve, which can be treated and processed at leisure, be more durable than something you'd had to preserve with a portable kit on the operating table with the clock ticking?
Or is there something about human tissue which makes it more suitable, more durable?
Thoughts please, folks.
Long term
It merits careful reading, the article - hence being in the "new advancements" as opposed to "valve choice"
It seems that there is still a preserving process going on during the operation and that it is still dead, preserved tissue that is being implanted. The estimate was around 20 years for lifetime (which is similar to the estimate for newer Bovine Pericardial Valves).
Now, I'd be interested to know more about the precise mechanism by which such a valve might calcify. The medical wisdom is that calcification is in part a slow, low level rejection process by the body. Would this preserved tissue be immume from this, to some extent? I don't know.
It's possible that the preservative might make the body treat it like any other tissue. In which case, one must ask if there is merit in the process at all. Would a bovine valve, which can be treated and processed at leisure, be more durable than something you'd had to preserve with a portable kit on the operating table with the clock ticking?
Or is there something about human tissue which makes it more suitable, more durable?
Thoughts please, folks.
J
JohnnyV_46
I think "Red Wing" made my new Aortic Valve...those things last forever on my feet. I think if it's dead tissue,I'll stick with the Tougher Cow material.... I am still alive after 10 months, the 19th of this month....Still can't bring myself to eat Beef as It makes me feel like a Cannibal.
Joe Cool
Well-known member
JohnnyV_46 said:
That's why I won't get a porcine valve, I like ham
The quote at the beginning of the article contradicts the one at the end."The surgeon made a replacement heart valve from my own tissue - and it will last forever"
"Using the patient?s own tissue may well be the ideal valve if its durability is proved. It is expected that the pericardium valve will last twenty years."
It is the unknown, like the old "bottomless lake". The guy had a thousand feet of line and the lake was 1010, so he never hit bottom, thus the lake was "bottomless".
Anyway, I "think" that someday soon they will figure out how to grow these valves, or using stem cells make these "processed" valves live. In the mean time . . . ?All we have to decide is what to do with the time that is given to us."
Deboraginastewart, our member from Brazil, had a valve fashioned during surgery from dura mater when she was quite young (fifteen years old, I believe). It was placed on a stainless steel framework. It lasted for fifteen years, if I've remembered the correct one.
The notion of fashioning a valve in flagrante chirurgia from the patient's own flesh is neither new nor untested. As I have been introduced to the issues of pericardial constriction, I would be concerned how it might affect the remainder of that tissue.
It would have been more thrilling for me if the tissue remained alive. Dead tissue, even your own, is not proof from calcification. The more interesting valves are those that allow your own tissue to gorw over them. Live, healthy tissue on a good, working valve should slow or possibly eliminate calcification.
Best wishes,
The notion of fashioning a valve in flagrante chirurgia from the patient's own flesh is neither new nor untested. As I have been introduced to the issues of pericardial constriction, I would be concerned how it might affect the remainder of that tissue.
It would have been more thrilling for me if the tissue remained alive. Dead tissue, even your own, is not proof from calcification. The more interesting valves are those that allow your own tissue to gorw over them. Live, healthy tissue on a good, working valve should slow or possibly eliminate calcification.
Best wishes,
