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  1. Bill B

    Heavy lifting post surgery......

    I had quite a bit of aorta replaced as well as my aortic valve. After the initial recovery period of 3 months ALL exercise restrictions were removed. Unless you have some other condition or the repair work was not complete, it would be unusal to have restrictions for life.
  2. Bill B

    Question about Anuerysm symptoms

    Doctors as well as the nurse practitioner are saying the pain is not related to your aneurysm. Aneurysms are asymptomatic until something really bad is happening, like disection. Yours has not done that. That would constitute a medical/surgical emergency. So, I would be looking for other...
  3. Bill B

    Sleeping post op

    Lots of people seem to use a recliner initially after discharge home. I didn't. I sleep on my side and I used a couple of pillow stacked to support my upper arm and chest in the hospital and at home and had zero problems in terms of stress on my sternum or discomfort. I used a recliner to...
  4. Bill B

    How's this for being sensitive?

    The effects of vitmain K can be faily rapid in high doses. I'm not sure how long the effects last. The pharmcodymanics of warfarin and the clotting factors it effects are complex and very hard to summarize. There is a cascade of different factors, each with different chacteristics in terms of...
  5. Bill B

    Not sure what to think, I NEED you guys AGAIN!

    Nice to hear, and he said all the right things about your anemia in relation to your valve, although, as I said, surgeons take what is rather severe anemia far too lightly. It SHOULD resolve, but yours seems rather marked (needing 2 units 2 weeks post-op), so I would work with your local doc to...
  6. Bill B

    Endocarditis False Alarm (I HOPE!)

    Good work getting this sorted in short order.:thumbup:
  7. Bill B

    Not sure what to think, I NEED you guys AGAIN!

    Yeah, two weeks is very early. Anemia is common post-OHS and over all poorly treated due to the limited blood supply and the historic fear of transmission of disease via other people's blood. In the month prior to surgery I donated 2 units of my own blood designated for me only. When I became...
  8. Bill B

    Not sure what to think, I NEED you guys AGAIN!

    Don't blame the valve just yet. Significant anemia like you have is very rare with hemolysis due to mechanical valves. Yes, there is a degree of hemolysis from mechanical valves, but usually this results in subclinical (not detectable) anemia IF you get enough iron in your diet. Anemia...
  9. Bill B

    Taro warfarin question

    That is the standard. It has been that way since the late 90s. I re-checked it when you asked to make sure it hasn't changed. The FDA is basically saying that any change in response seen with that potential variation is not clinically significant. This has come under fire since the day it...
  10. Bill B

    Taro warfarin question

    I provided a link to a presentation given by FDA staff that confirms the range allowed (-20 to +25%). It is a point of controversy. Warfarin is considered a "narrow therapeutic range" drug, and that variation range is still considered safe by the FDA.
  11. Bill B

    Endocarditis False Alarm (I HOPE!)

    Yes, scary stuff, but it sounds like you're ontop of it.
  12. Bill B

    How's this for being sensitive?

    Well, the experiment continues....I ate a huge spinach salad yesterday. Probably 1000mcg of vitmain K. Sometime early next week I'll get another INR. My hope is that my INR is about 2.5, down from 2.9. If it is, I'll continue to eat a mound of spinach about once a week, and continue with the...
  13. Bill B

    Pre-natal screening for BAV?

    Yeah, I wouldn't do it based on a midwife suggestion, but I might if my cardiologist or a geneticist recommended it. I've looked at the inheritance information, which is actually limited. The way the data are expressed is confusing and makes it sound very high (89% "heritability" in one...
  14. Bill B

    Got another echo last week and follow up with doc today. Got bad news!

    Sounds quite similar to me, but mine was 1.1 at detection, 0.9 nine months later and 0.7 three months after that. Surgery 3 months after the last echo. My ascending aorta was about the same size (borderline). I had everything fixed. This is a lot faster than the statistical average of 0.1cm...
  15. Bill B

    Pre-natal screening for BAV?

    Well, this is a fair question. The heritability of BAV is "high" in the view of geneticists, so there is support for echo screening, at least at some point. Early in life the condition is usually benign, so I don't see a significant benefit to prenatal screening, unless perhaps you have close...
  16. Bill B

    How rapidly did your aortic symptoms develop and worsen ?

    Well, that sounds better. The timing of surgery is a subject for debate. Honestly, there is no clear proof that doing it when still asymptomatic really improves the outcomes, unless you are comparing to somebody who is terribly compromised, but I and many others hope we got a better result by...
  17. Bill B

    Is there a way to predict dosing changes if adding K to the diet?

    This is totally individual. Change-measure-change some more-measure some more. It's not even linear (2x change in dose does not lead to 2x change in result).
  18. Bill B

    How's this for being sensitive?

    No, same bottle of warfarin 3mg. I get 90 days supply at a time. I just changed one day/week from 1/2 pill to 1 pill in the middle of the same bottle.
  19. Bill B

    Taro warfarin question

    You could write a Ph.D. thesis on this. Generic warfarin formulations are tested for "bioequivalence" to a standard but not to each other. There is a -20/+25% variation allowed from the standard in drug blood level area under the curve and peak. So, what this means is one product may be more...
  20. Bill B

    How's this for being sensitive?

    Well, being sensitive isn't all bad, is it Bina? Here are the definitive vitamin K content references. By content: https://www.ars.usda.gov/SP2UserFiles/Place/12354500/Data/SR24/nutrlist/sr24w430.pdf Alphabetical...
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