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The Indian testing group is definitely smaller than US (I remember that, though can't find the pricise number now), but that compensates with shorter term of the trial, after which everyone is welcome to the surgery, as I understand. India alone has 1,4 bn population, and count the medical...

Maybe not anymore. Maybe the new polymeric valve will provide a much more definitive treatment than before, and the only major menace for valvular patients will be aortic aneurysm.

Kkch.i Here are the links to the US Early Feasibility Studies for aortic and mitral surgical Foldax valves. As stated there, the estimated Study Completion Date is December 2026 and December 2025. Will the valves be cleared for use after these studies, I am not sure, don't know the usual...

Jtucker33 Just out of interest, did you have aortic stenosis, or regurgitation?

Congratulations, eagerly waiting.

Looks quite generic to me...

@acki46 As for symptoms, what about forceful (bounding) pulse? Did you feel it, or do you feel it now?

I find quite soothing his repeated words "there's nothing to be afraid of" and that his surgery was pain-free. Yes, he didn't get a full cut, but still.

acki46 Thanks for your story. I'd like to ask you: did you take any meds regularly before the surgery? did you have any heart-related symptoms before the surgery? I wish you all the best.

Probably you had both stenosis and regurgitation. Best of luck to you!

I am confused, as your profile info says "regurgitation", not stenosis. I am in the waiting room for now.

Congratulations! May I ask, did you have any degree of stenosis, or it was pure regurgitation? How are you doing now?

bb81 Level 1 (mild) regurgitation is of no real concern in any valve. Level 2 (moderate) varies quite broadly in volume and severety, generally the aortic valve surgery is indicated starting from moderate-severe and worse. Often the eccentric jet adds to the margin of error in quantifying the...

I think it depends if the aortic root is involved in the aneurysm. The coronary arteries are connected to the root and need to be reattached to the new prosthetic aorta. This is the delicate step in a surgery, there's no need to risk and leave what few is left below the coronary arteries, since...

Actually Foldax aortic valve has the cuff outside diameter of up to 36mm, so a large annulus should be covered, and intra-annular implantation should be possible too, which gives annulus size of 36mm. Good.

Thanks for the story. Had you considered any options other than the mechanical valve? Is your ascending aorta normal, or enlarged?

Hello, what's your problem - regurgitation or stenosis?

In case of polymeric flexible valves I can see why there may be a difference in engineering between aortic and mitral valves. For example wider and/or shorter valve may require more strength in the flexible cusps.

So far Foldax only has valves up to 27mm. Only mitral are bigger.

Of course not the human mitral valve, but the mitral mechanical prosthesis. Here's example Use of an inverted On-X mitral valve in the aortic position in a resource limited setting - PubMed They call 30mm annulus "excessively large". @pellicle Yes, backward facing.