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The dream of lower INT on On-X is just a pipe dream. The main cause of thrombosis is platelet activation due to the impact of the mechanical leaflets and blood. It is not materials or how smooth the surface is. Why would a doctor who is comfortable administering INR range of 2.0 through 3.5...

Great durability 15/20 years compared to lifetime durability? No one says tissues are sub optimal in of themselves. They are sub optimal depending on the patient. There is a higher failure risk of tissue in younger patients. More tissues are transplanted because heart disease, for the most...

A fast heart rate is not necessarily afib. If you have a mechanical valve you should be able to hear irregular heartbeats, if it is fast and the rhythm is completely off then it is afib and it is not the skipped beats that you feel like an elevator dropped. you may/may not have palpitations...

Transcatheter addresses one of 3 valves at the moment, with time it may address all valves and be the general standard. I also understand at the moment it addresses stenotic valves not other types of valve failures but again with time, they will get there. A replacement valve on top of an old...

You get a mechanical valve, you will hear the ticking - there is no two way around it, question is how soon will you be able to adjust to not hearing it. You can hear your wall clock ticking if you focus on it but at some point you learned to ignore the noise and focus on other things. In your...

I have read with great interests the valve selections in here: mechanical versus bioprosthetic; On -X, St Jude; Masters, Regents... Not to mention blood dynamics and flow over valves... It's good to know we have choices today but an argument on efficiency, blood flow, valve function to me...