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  1. Nocturne

    The Future of Valve Choice?

    Ah. YOU'RE the one I've been remembering all of this time. We don't see you post here anymore. I hope you are well. I want you to know that I think I have a degree of understanding of why someone who was born with a physical heart defect might feel some animosity towards someone who was not...
  2. Nocturne

    Lp(a) of 390 nmol/L!

    From the above, it would seem that my Lp(a) of 390 nmol/L could be converted as something between 137 and 211, depending on particle size(s). The recommended conversion would be 162 mg/Dl. That's the sort of high you get from having homozygous alleles for bad Lp(a).
  3. Nocturne

    Lp(a) of 390 nmol/L!

    OK, so not from 150 to mid 20s. But yes, very impressive for a factor that is supposedly intractable. And yes, I am in the States where apparently we have decided to pretend that Lp(a) is not a thing. A word about conversions from the Lp(a) Foundation forum: * * * * * Converting Lp(a) from...
  4. Nocturne

    Lp(a) of 390 nmol/L!

    Agian, what level was your Lp(a) prior to treatment? How far down did it go? I have looked around on the Lp(a) Foundation forum and seen a few people claiming to have Lp(a) levels in excess of 150 mg/Dl. There really are some people with crazy high Lp(a) levels out there. It is unfortunate but...
  5. Nocturne

    Lp(a) of 390 nmol/L!

    So this is interesting... Checked the forums on the Lp(a) foundation website and learned that you can find the SNPs associated with high Lp(a) in the raw data from 23andme (which I have already gotten). Checked my data and found that I am homozygous for one of the alleles associated with high...
  6. Nocturne

    Lp(a) of 390 nmol/L!

    Agian, I found the same converter and it seems wonky. I'm not sure how 109 makes any sense when it is double the "extreme risk" cutoff in mg/dl and 390 nmol/L is more than triple the same cutoff of 125 nmol/L. Paleowoman's calculation of 150-something really does make more sense. In any event...
  7. Nocturne

    Lp(a) of 390 nmol/L!

    Looks like you did not finish your first sentence there. I read the whole blurb on Fenofibrate but I must have missed the part where it mentioned how it can bring down Lp(a). It is evident to me that my heart issues were caused primarily by FH and extremely extremely high Lp(a). I just found...
  8. Nocturne

    Lp(a) of 390 nmol/L!

    156 mg/dL is a bit more than triple the "very high risk" cutoff, which is what 390 nmol/L is. So Paleowoman's conversion makes sense. So if I cut it by 66% it is still "extremely high". From what I have read, my Lp(a) level combined with extant AS and CAD would qualify me for apheresis...
  9. Nocturne

    Lp(a) of 390 nmol/L!

    Wait -- Fenofibrate INCREASES Lp(a)? Why would I want to take that? http://journals.lww.com/cardiovascularpharm/Fulltext/2005/10000/Effect_of_Fenofibrate_on_Lipoprotein_a__in.2.aspx I mean sure, my triglycerides are great, actually, so maybe this doesn't apply to me, but... Something seems...
  10. Nocturne

    Lp(a) of 390 nmol/L!

    I have been reading that it is not possible to convert the measurement in nmol/L to mg/dl for some reason. In any event I have yet to find a converter or conversion formula anywhere online. So I am not really sure if your friend is higher than me -- although it is entirely possible. 80 is...
  11. Nocturne

    Lp(a) of 390 nmol/L!

    Did not see this entire post for some reason. I am glad the Evolucumab worked for you, but see above. Will look into DHEA; have already read some about it on the testosterone forum I frequent. Doc told me that the Ornish/Esselstyn data was scant, that Esselstyn had been using the same small...
  12. Nocturne

    Lp(a) of 390 nmol/L!

    Thank you,Agian, but this report would seem to question the validity of your calculations: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067066/ As for Niacin: "At present, no effective drug therapy is available for Lp(a) – nicotinic acid was withdrawn from the market in Europe after two...
  13. Nocturne

    Lp(a) of 390 nmol/L!

    OK I'm seeing a 30% reduction in Lp(a) from Repatha? I know this is a relatively new drug, but it still feels odd that even the Lp(a) foundation doesn't seem to mention it on their website. I cannot find a conversion from nmol/L to mg/dl for Lp(a) anywhere online. Which is frustrating. But...
  14. Nocturne

    Lp(a) of 390 nmol/L!

    "In clinical trials, in patients with primary hypercholesterolaemia [Heterozygous familial hypercholesterolaemia (HeFH) and atherosclerotic cardiovascular disease (CVD)], Repatha reduced LDL-C, TC, ApoB, non-HDL-C, TC/HDL-C, ApoB/apolipoprotein A1 (ApoA1), VLDL-C, TG and Lp(a), and increased...
  15. Nocturne

    Lp(a) of 390 nmol/L!

    Sorry, I've just... I've been carrying that for a while now. More info on Lp(a) as a cause of aortic stenosis here: http://www.jlr.org/content/57/6/917 It seems that most people dealing with AS at a younger age have bicuspid valve. When I first came here, I felt very alone and confused...
  16. Nocturne

    Lp(a) of 390 nmol/L!

    Agian, as far as I know, Evolocumab has no effect on Lp(a), bad Lp(a) is highly heritable, and CAC scores go up steadily over time and do not "freeze". If you can find me any actual data to the contrary I would like to see it. I do have low T and am being treated for it. As it turns out, TRT is...
  17. Nocturne

    Lp(a) of 390 nmol/L!

    Agian, as far as I know, Evolocumab has no effect on Lp(a), bad Lp(a) is highly heritable, and CAC scores go up steadily over time and do not "freeze". If you can find me any actual data to the contrary I would like to see it. I do have low T and am being treated for it. As it turns out, TRT...
  18. Nocturne

    Lp(a) of 390 nmol/L!

    OK - a ray of hope: http://www.lipoproteinafoundation.org/page/AkceaPhaseII If all goes well there could be a new Lp(a) lowering drug on the market in a few years -- and this one seems really effective too. Note that elevated levels of Lp(a) are significantly associated with calcific aortic...
  19. Nocturne

    Lp(a) of 390 nmol/L!

    Just got the results of two tests that had not come back before my meeting with my cardio doc. One was good except my Large HDL count was much too low (despite HDL reaching 45, which I had seen as a bit of unexpected good news). The other was my lipoprotein A level. A score of 75 nmol/L or...
  20. Nocturne

    Right bundle branch block

    I have been astounded by what cardio docs DON'T know, sometimes. Found an article about coronary artery calcium recently that had registered (docs-only) comments, and it was almost scary how many of the commenting docs just didn't have a clue about some really basic stuff; some of them were...
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