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Very interesting read, in part because everything else I have read has indicated that statins INCREASE Lp(a) levels. In fact, even in the article you linked to above, we get this: "Interestingly, only in long-term statin use in some stratifications, were there significantly reduced Lp (a)...

Dornole, I do appreciate your concern, but I've already gone the therapy route. Went with the same guy I saw back when I got divorced, oh, 18 years ago. And just like that time, I quickly realized that I prefer changing the things I can't accept to accepting the things I can't change -- and...

No apology necessary, cldlhd. I think you are pretty much in the right. As for the PCSK9 inhibitors, the companies know they can't prevail in the long run, as these meds save lives -- they're just slowing the process of their being forced to pay down to a crawl. A number of people will die or...

The AHA also does not recommend actually giving niacin to high Lp(a) patients, in large part due to recent studies that indicated niacin had no effect on outcomes for most people. From the the link you provided: "Niacin reduces Lp(a) levels by up to 30% to 40% in a dose‐dependent manner and in...

AZ Don, I agree with you (love your state, BTW). And I have come to enjoy the taste of many healthy foods -- just learned how to make a really nice eggplant casserole, and my wife cooks a mean black bean soup. And those two drinks a day are nice, as is the small piece of dark chocolate. I'm...

Diet and exercise cannot affect Lp(a) levels, but they can affect the usual markers and those matter even more when your Lp(a) is high. Plus I already have extreme coronary artery disease for someone of my age -- the CAC score of a 70 year old man at 42. So, knowing what I know about my...

I am curious about what the tone of your response here was meant to be. Of course we can always find people who would trade places with us "in a heartbeat". In my opinion, anyone with severe epidermolysis bullosa (look it up) has more right to be angry, upset, and depressed than any of us. But...

Did you have a bicuspid aortic valve, or a regular tricuspid one? Did you at any time have your Lp(a) tested, or have a coronary CT scan? There is a reason I am asking.

My advice to you is to have a coronary CT scan done. If you have a very unusual amount of coronary artery calcium (CAC), then you might lean more towards a tissue valve because there is some evidence that Warfarin accelerates coronary arterial calcification. If you don't have much CAC for your...

Enjoys life "exuberantly"? When pretty much everything they enjoy will hasten their death? At this stage, I'm being irresponsible if I eat anything other than a leaf or a twig, drink anything other than water, or do anything other than exercise. God forbid I sit down to enjoy a movie or a book...

Met with a genetic counselor and the cardiologist she works with the other day. They were both very nice people, and had clearly taken the time to read up on Lp(a) and the genetic component I had mentioned when I set up the appointment (they both said they had read up on it because they knew...

Blake, how have you been doing? I know that afib with a prosthetic valve is no joke. Have they gotten it under control?

Respect -- I forgot you were 81. Congrats! Your point seems to be that we can't know when we'll die. I never disagreed with that point. BUT... I'm assuming that you're not expecting to see 200. There is a reason for that. When you see a 20 year old kid, you probably expect he's got a long...

Probably if I make it to 80 I'll feel exactly the same way you do.

What exactly do you mean by that, Agian? Is it just a matter of calling me "stupid" because you disagree with my viewpoint but have no real argument against it?

Yeah, I never got this one. If an ordinary person my age could expect to live another 40 years or so, and I get told that I have a condition that means I can only expect another 25 years or so, "But don't worry -- you could still die in a car accident tomorrow" seems like a pretty bizarre and...

Nah, just keep repeating that everything's fine. https://m.youtube.com/watch?v=g3qkbc28R_I

And JESUS, Tubaman, why did your doc advise against testosterone replacement? TRT is known to lower Lp(a), and Lp(a) accelerates the progression of AVS! Too many docs have no clue about TRT (mine was down to a near-castrate 135 when we caught it and put me on clomid therapy, which brought it...

There is some evidence that lowering Lp(a) might slow down progression of CAVS, and perhaps AVS that results from a BAV as well. There is a study wrapping up at McGill University right now that is looking into this. IMO anyone with AVS should get their Lp(a) checked, as well as coronary artery...

Shirley, forgive me, I do not know much about your story. I noticed that you had CABG at the age of 41 -- that's very unusual. Do you know what caused the need for it?