pellicle
Professional Dingbat, Guru and Merkintologist
Morning
a couple of interesting points here.
so my first question is are you on Metoprolol succinate (Ms) or tartrate (Mt)?
As you may know, I've started Mt as of about May this year due to some (I like to call them passive aggressive) ectopic beats which then progress to full blown tachycardia (more on that in a tic) and my HR just decides to hit 140 and stay there ... I tried cycling it out but when I got back it didn't settle ... and I can't do that 24/7 so I ended up getting the schitz with it and going to the hospital who diagnosed (agreed with mine actually) that I needed something and we settled on Mt (half a 50mg tablet twice daily).
This has a shorter half life (consult the two layer complex graph below)
as observed in Wikipedia:
The different salt versions of metoprolol – metoprolol tartrate and metoprolol succinate – are approved for different conditions and are not interchangeable
and shown above the interactions of each and the (bottom half of the graph) reduction in HR is more marked with tartrate but reduces in effect more quickly when at (something like) 12 hours succinate continues to provide a suppressing effect.
I've found that being on tartrate allows me to take Mt in the evening, get a proper restful sleep (without being shaken awake by passive aggressive ectopics) followed by unignorable high HR and a pounding headache if left ignored ... presumably by the blood not getting back into circulation properly (presumably because of my vascular occlusion gifted as a side effect in the last redo surgery - yah lets promote redos to infinity).
The benefit is that I can go on a cycle in the morning (when I typically do it in summer to avoid the heat, but catch more insects) and when I'm cooling down on return home pop half an M tablet and move on till dinner approaches in otherwise good shape.
So, perhaps this will help if anyone who's "unable to push through" their M effect when wanting to exersize and choosing Mt or Ms.
Of course consult your Dr, not just listen to some bozo on the internet who hasn't got a clue what he's talking about.
This leads me to my Qn for @Superman : what was causal in your move to M? Was it something like mine in a post surgery (like you've had fifty or something now right?) or was it something else?
As mine emerged some 10 years after my last OHS (or rapeNscrape debridement) {and someone sure took my bride a few months before!!} I would wonder if its actually (in my case) a symptom of COVID exposure (I was double vaxxed early) which I can't rule out (and some sites suggest is possible post C as a long C symptom) I found this site interesting
https://www.gosh.nhs.uk/conditions-...ons-we-treat/inappropriate-sinus-tachycardia/
[underline mine]
and given the anatomy
its a shoe in that after 3 surgeries that node is likely influenced into being abnormal in some way by scar tissue on my heart around that aortic valve (among other causes).
Or (in my case) its my bacteria come out from their polysaccharide biofilm hide to play the last part of hide and seek
dunno.
a couple of interesting points here.
... Have been for 13 years now. One if the issues I read here is that people can’t push their heart rate high enough when exercising while on the drug. Thankfully I haven’t had that issue.
so my first question is are you on Metoprolol succinate (Ms) or tartrate (Mt)?
As you may know, I've started Mt as of about May this year due to some (I like to call them passive aggressive) ectopic beats which then progress to full blown tachycardia (more on that in a tic) and my HR just decides to hit 140 and stay there ... I tried cycling it out but when I got back it didn't settle ... and I can't do that 24/7 so I ended up getting the schitz with it and going to the hospital who diagnosed (agreed with mine actually) that I needed something and we settled on Mt (half a 50mg tablet twice daily).
This has a shorter half life (consult the two layer complex graph below)
![1666302653803.png 1666302653803.png](https://cdn2.imagearchive.com/valvereplacement/data/attach/2/2208-1666302653803.png)
as observed in Wikipedia:
The different salt versions of metoprolol – metoprolol tartrate and metoprolol succinate – are approved for different conditions and are not interchangeable
and shown above the interactions of each and the (bottom half of the graph) reduction in HR is more marked with tartrate but reduces in effect more quickly when at (something like) 12 hours succinate continues to provide a suppressing effect.
I've found that being on tartrate allows me to take Mt in the evening, get a proper restful sleep (without being shaken awake by passive aggressive ectopics) followed by unignorable high HR and a pounding headache if left ignored ... presumably by the blood not getting back into circulation properly (presumably because of my vascular occlusion gifted as a side effect in the last redo surgery - yah lets promote redos to infinity).
The benefit is that I can go on a cycle in the morning (when I typically do it in summer to avoid the heat, but catch more insects) and when I'm cooling down on return home pop half an M tablet and move on till dinner approaches in otherwise good shape.
So, perhaps this will help if anyone who's "unable to push through" their M effect when wanting to exersize and choosing Mt or Ms.
Of course consult your Dr, not just listen to some bozo on the internet who hasn't got a clue what he's talking about.
This leads me to my Qn for @Superman : what was causal in your move to M? Was it something like mine in a post surgery (like you've had fifty or something now right?) or was it something else?
As mine emerged some 10 years after my last OHS (or rapeNscrape debridement) {and someone sure took my bride a few months before!!} I would wonder if its actually (in my case) a symptom of COVID exposure (I was double vaxxed early) which I can't rule out (and some sites suggest is possible post C as a long C symptom) I found this site interesting
https://www.gosh.nhs.uk/conditions-...ons-we-treat/inappropriate-sinus-tachycardia/
What causes inappropriate sinus tachycardia?
There are many theories as to the cause of inappropriate sinus tachycardia (IST) and more research is needed to confirm the cause(s). One theory is that the sinoatrial (SA) node is abnormal in some way, or that the person is over-sensitive to the hormone adrenaline, which causes the heart to beat faster. It could also be caused by a disturbance to the autonomic nervous system – the part of the nervous system responsible for ‘automatic’ functions such as heart rate and breathing.[underline mine]
and given the anatomy
![1666303652463.png 1666303652463.png](https://cdn2.imagearchive.com/valvereplacement/data/attach/2/2209-1666303652463.png)
its a shoe in that after 3 surgeries that node is likely influenced into being abnormal in some way by scar tissue on my heart around that aortic valve (among other causes).
Or (in my case) its my bacteria come out from their polysaccharide biofilm hide to play the last part of hide and seek
dunno.
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